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10/30/2024 10:05:55 AM | Browse: 74 | Download: 590
Publication Name World Journal of Clinical Oncology
Manuscript ID 99240
Country United States
Received
2024-07-17 17:16
Peer-Review Started
2024-07-17 17:16
First Decision by Editorial Office Director
2024-08-05 21:16
Return for Revision
2024-08-06 11:37
Revised
2024-09-09 12:37
Publication Fee Transferred
Second Decision by Editor
2024-10-11 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-10-11 09:16
Articles in Press
2024-10-11 09:16
Edit the Manuscript by Language Editor
2024-10-16 14:58
Typeset the Manuscript
2024-10-28 08:53
Publish the Manuscript Online
2024-10-30 10:05
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Proton pump inhibitors and all-cause mortality risk among cancer patients
Manuscript Source Invited Manuscript
All Author List Arunkumar Krishnan, Carolin Victoria Schneider and Declan Walsh
ORCID
Author(s) ORCID Number
Arunkumar Krishnan http://orcid.org/0000-0002-9452-7377
Carolin Victoria Schneider http://orcid.org/0000-0002-6728-9246
Declan Walsh http://orcid.org/0000-0002-9310-1729
Funding Agency and Grant Number
Corresponding Author Arunkumar Krishnan, MD, Assistant Professor, Department of Supportive Oncology, Atrium Health Levine Cancer, 1021 Morehead Medical Drive, Suite 70100, Charlotte, NC 28204, United States. dr.arunkumar.krishnan@gmail.com
Key Words Outcome; Carcinoma; Proton pump inhibitors; Malignancy; Mortality; Histamine-2 receptor antagonists; Cancer; All-cause mortality
Core Tip Proton pump inhibitors (PPIs) are commonly used medications. Recent studies have raised concerns regarding increased all-cause and cause-specific mortality with PPIs. However, limited studies have addressed this issue in cancer patients. In addition, an association between PPI and the mortality risk in unselected cancer populations remains uncertain. We investigated the association between PPI use and all-cause mortality in patients diagnosed with cancer. PPI use among cancer patients was associated with a higher risk of all-cause mortality compared to non-users or histamine-2 receptor antagonist users. These results strongly suggest the need for cautious use of PPIs in cancer patients and suggest that alternative treatments should be considered when clinically feasible.
Publish Date 2024-10-30 10:05
Citation

Krishnan A, Schneider CV, Walsh D. Proton pump inhibitors and all-cause mortality risk among cancer patients. World J Clin Oncol 2025; 16(1): 99240

URL https://www.wjgnet.com/2218-4333/full/v16/i1/99240.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i1.99240
Full Article (PDF) WJCO-16-99240-with-cover.pdf
Manuscript File 99240_Auto_Edited_085855.docx
Answering Reviewers 99240-answering-reviewers.pdf
Audio Core Tip 99240-audio.mp4
Biostatistics Review Certificate 99240-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 99240-conflict-of-interest-statement.pdf
Copyright License Agreement 99240-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 99240-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 99240-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 99240-non-native-speakers.pdf
Supplementary Material 99240-supplementary-material.pdf
Peer-review Report 99240-peer-reviews.pdf
Scientific Misconduct Check 99240-scientific-misconduct-check.png
Scientific Editor Work List 99240-scientific-editor-work-list.pdf
CrossCheck Report 99240-crosscheck-report.pdf