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Articles Published Processes
9/13/2024 3:22:17 AM | Browse: 60 | Download: 149
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Received |
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2024-07-18 10:46 |
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Peer-Review Started |
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2024-07-18 10:46 |
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To Make the First Decision |
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Return for Revision |
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2024-08-05 21:14 |
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Revised |
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2024-08-11 08:48 |
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Second Decision |
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2024-08-26 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-08-26 06:01 |
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Articles in Press |
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2024-08-26 06:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2024-09-01 21:38 |
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Typeset the Manuscript |
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2024-09-09 06:42 |
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Publish the Manuscript Online |
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2024-09-13 03:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Peroxisome proliferator-activated receptor agonists: A new hope towards the management of alcoholic liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Siva Sundara Kumar Durairajan, Abhay Kumar Singh and Ashok Iyaswamy |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Siva Sundara Kumar Durairajan, MSc, PhD, Associate Professor, Department of Microbiology, School of Life Sciences, Central University of Tamil Nadu, Neelakudi, Tiruvarur 610005, India. d.sivasundarakumar@cutn.ac.in |
| Key Words |
Alcoholic liver disease; Peroxisome proliferator-activated receptors; Peroxisome proliferator-activated receptors agonists; Liver fibrosis; Inflammation; Metabolic regulation; Hepatoprotection |
| Core Tip |
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors, including PPARα, PPARγ, and PPARβ/δ. They regulate vital factors in the development of alcoholic liver disease (ALD), like lipid metabolism, inflammation, and fibrosis. PPAR agonists have the potential to manage ALD. In recent preclinical and clinical trials, PPAR agonists have revealed their potency to eliminate liver steatosis, improve insulin receptor sensitivity, and diminish inflammation and fibrosis. However, to confirm their effectiveness and reveal side effects, larger clinical trials in ALD must be conducted. This article, therefore, raises the need for further study and debate on the application of PPAR agonists for ALD management. |
| Publish Date |
2024-09-13 03:22 |
| Citation |
<p>Durairajan SSK, Singh AK, Iyaswamy A. Peroxisome proliferator-activated receptor agonists: A new hope towards the management of alcoholic liver disease. <i>World J Gastroenterol</i> 2024; 30(35): 3965-3971</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i35/3965.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i35.3965 |
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