BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/21/2025 10:13:00 AM | Browse: 65 | Download: 92
Publication Name World Journal of Transplantation
Manuscript ID 99287
Country Italy
Received
2024-08-14 02:25
Peer-Review Started
2024-07-18 21:32
To Make the First Decision
Return for Revision
2024-10-23 07:18
Revised
2024-11-07 15:42
Second Decision
2025-01-10 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-01-11 08:47
Articles in Press
2025-01-11 08:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-08 04:05
Publish the Manuscript Online
2025-02-21 10:13
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Basic Study
Article Title Haemoadsorption cartridge connected to the machine perfusion for donation after circulatory death porcine liver marginal grafts
Manuscript Source Invited Manuscript
All Author List Irene Scalera, Rossana Franzin, Alessandra Stasi, Antonino Castellaneta, Enrico Fischetti, Giulia Morelli, Margherita Raele, Emilio Panetta, Andjela Kurevija, William Pulga, Mauro Atti and Loreto Gesualdo
ORCID
Author(s) ORCID Number
Irene Scalera http://orcid.org/0000-0002-4244-9311
Rossana Franzin http://orcid.org/0000-0001-7907-7614
Alessandra Stasi http://orcid.org/0000-0003-3652-3623
Loreto Gesualdo http://orcid.org/0000-0002-4861-0911
Funding Agency and Grant Number
Corresponding Author Irene Scalera, MD, PhD, Hepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, Piazza G Cesare 11, Bari 70124, Puglia, Italy. irenescalera@gmail.com
Key Words Liver donor; Machine perfusion; Sorbent cartridge; Donation after circulatory death; Cytokines; Ischemia-reperfusion-injury
Core Tip Marginal donation after circulatory death liver grafts are carefully used to fight the constant shortage of donors. Clinically, the worst outcomes are mainly related to severe ischemia-reperfusion-injury and the dangerous effect of various inflammatory cytokines (CK). The machine perfusion (MP) is a promising device to rescue these grafts. Recently, a new ex-situ MP device incorporating a filter cartridge to the machine has been considered. It was tested on pigs, and it appears to reduce the CK during the treatment of standard liver grafts. The purpose of the study was the analysis of the role of the CK cartridge connected to the MP and used to preserve extremely marginal pig grafts during processing in the MP. The results were analyzed biochemically and histologically.
Publish Date 2025-02-21 10:13
Citation <p>Scalera I, Franzin R, Stasi A, Castellaneta A, Fischetti E, Morelli G, Raele M, Panetta E, Kurevija A, Pulga W, Atti M, Gesualdo L. Haemoadsorption cartridge connected to the machine perfusion for donation after circulatory death porcine liver marginal grafts. <i>World J Transplant</i> 2025; 15(2): 99287</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i2/99287.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i2.99287
Full Article (PDF) WJT-15-99287-with-cover.pdf
The ARRIVE Guidelines 99287-The-ARRIVE-Guidelines.pdf
Manuscript File 99287_Auto_Edited_011035.docx
Answering Reviewers 99287-answering-reviewers.pdf
Audio Core Tip 99287-audio.m4a
Biostatistics Review Certificate 99287-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 99287-conflict-of-interest-statement.pdf
Copyright License Agreement 99287-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 99287-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 99287-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 99287-non-native-speakers.pdf
Peer-review Report 99287-peer-reviews.pdf
Scientific Misconduct Check 99287-scientific-misconduct-check.png
Scientific Editor Work List 99287-scientific-editor-work-list.pdf
CrossCheck Report 99287-crosscheck-report.pdf