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Articles Published Processes
2/21/2025 10:13:00 AM | Browse: 65 | Download: 92
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Received |
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2024-08-14 02:25 |
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Peer-Review Started |
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2024-07-18 21:32 |
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To Make the First Decision |
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Return for Revision |
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2024-10-23 07:18 |
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Revised |
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2024-11-07 15:42 |
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Second Decision |
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2025-01-10 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-01-11 08:47 |
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Articles in Press |
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2025-01-11 08:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-02-08 04:05 |
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Publish the Manuscript Online |
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2025-02-21 10:13 |
ISSN |
2220-3230 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Basic Study |
Article Title |
Haemoadsorption cartridge connected to the machine perfusion for donation after circulatory death porcine liver marginal grafts
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Manuscript Source |
Invited Manuscript |
All Author List |
Irene Scalera, Rossana Franzin, Alessandra Stasi, Antonino Castellaneta, Enrico Fischetti, Giulia Morelli, Margherita Raele, Emilio Panetta, Andjela Kurevija, William Pulga, Mauro Atti and Loreto Gesualdo |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Irene Scalera, MD, PhD, Hepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, Piazza G Cesare 11, Bari 70124, Puglia, Italy. irenescalera@gmail.com |
Key Words |
Liver donor; Machine perfusion; Sorbent cartridge; Donation after circulatory death; Cytokines; Ischemia-reperfusion-injury |
Core Tip |
Marginal donation after circulatory death liver grafts are carefully used to fight the constant shortage of donors. Clinically, the worst outcomes are mainly related to severe ischemia-reperfusion-injury and the dangerous effect of various inflammatory cytokines (CK). The machine perfusion (MP) is a promising device to rescue these grafts. Recently, a new ex-situ MP device incorporating a filter cartridge to the machine has been considered. It was tested on pigs, and it appears to reduce the CK during the treatment of standard liver grafts. The purpose of the study was the analysis of the role of the CK cartridge connected to the MP and used to preserve extremely marginal pig grafts during processing in the MP. The results were analyzed biochemically and histologically. |
Publish Date |
2025-02-21 10:13 |
Citation |
<p>Scalera I, Franzin R, Stasi A, Castellaneta A, Fischetti E, Morelli G, Raele M, Panetta E, Kurevija A, Pulga W, Atti M, Gesualdo L. Haemoadsorption cartridge connected to the machine perfusion for donation after circulatory death porcine liver marginal grafts. <i>World J Transplant</i> 2025; 15(2): 99287</p> |
URL |
https://www.wjgnet.com/2220-3230/full/v15/i2/99287.htm |
DOI |
https://dx.doi.org/10.5500/wjt.v15.i2.99287 |
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