Publication Name	World Journal of Clinical Cases
Manuscript ID	99311
Country	China

Received	2024-10-28 09:24
Peer-Review Started	2024-07-19 14:13
To Make the First Decision
Return for Revision	2025-01-16 01:05
Revised	2025-01-27 17:52
Second Decision	2025-02-26 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-26 09:39
Articles in Press	2025-02-26 09:39
Publication Fee Transferred	2025-01-29 04:03
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-03 10:41
Publish the Manuscript Online	2025-03-19 06:12

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Successful treatment of depressed esophageal squamous papilloma with interferon- alpha 2a: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Jiong Jiang, Hai-Tao Shi, Jie Wu, Su-Mei Sha, Shang-Xuan Cai and Xin Liu
ORCID	Author(s) ORCID Number Jiong Jiang http://orcid.org/0000-0003-0386-4640 Hai-Tao Shi http://orcid.org/0000-0003-2354-5209 Jie Wu http://orcid.org/0000-0002-5821-9705 Xin Liu http://orcid.org/0000-0002-2773-4480
Funding Agency and Grant Number	Funding Agency Grant Number Key Research & Development Program of Shaanxi Province 2021SF-221
Corresponding Author	Jiong Jiang, PhD, Departmen of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an 710004, Shaanxi Province, China. jjangus712@163.com
Key Words	Papilloma; Esophagus; Interferon-alpha 2a; Human papillomavirus; Case report
Core Tip	Esophageal squamous papilloma (ESP) is a rare benign epithelial tumor of the esophagus, typically presenting with an exophytic and warty appearance, often measuring less than 5 mm in diameter. Endoscopic resection is regarded as the most effective treatment for these tumors. However, the complete resection rate remains low. In this paper, we reported a case of ESP located in the lower esophagus that exhibited an unusual depressed endoscopic appearance with a diameter approaching 2 cm, which showed significant therapeutic outcomes by recombinant human interferon-alpha 2a. Nevertheless, further validation of the efficacy of interferon treatment is necessary through larger-scale studies involving subsequent cases.
Publish Date	2025-03-19 06:12
Citation	<p>Jiang J, Shi HT, Wu J, Sha SM, Cai SX, Liu X. Successful treatment of depressed esophageal squamous papilloma with interferon- alpha 2a: A case report. <i>World J Clin Cases</i> 2025; 13(19): 99311</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i19/99311.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i19.99311

Full Article (PDF)	WJCC-13-99311-with-cover.pdf
CARE Checklist–2016	99311-CARE-Checklist-2016.pdf
Manuscript File	99311_Auto_Edited_065155.docx
Answering Reviewers	99311-answering-reviewers.pdf
Audio Core Tip	99311-audio.m4a
Conflict-of-Interest Disclosure Form	99311-conflict-of-interest-statement.pdf
Copyright License Agreement	99311-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99311-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	99311-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	99311-non-native-speakers.pdf
Peer-review Report	99311-peer-reviews.pdf
Scientific Misconduct Check	99311-scientific-misconduct-check.png
Scientific Editor Work List	99311-scientific-editor-work-list.pdf
CrossCheck Report	99311-crosscheck-report.pdf