Publication Name	World Journal of Hepatology
Manuscript ID	99338
Country	China

Received	2024-07-20 04:57
Peer-Review Started	2024-07-20 04:57
To Make the First Decision
Return for Revision	2024-08-15 20:49
Revised	2024-09-05 03:03
Second Decision	2024-09-23 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-23 11:19
Articles in Press	2024-09-23 11:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-27 02:03
Publish the Manuscript Online	2024-10-21 07:03

ISSN	1948-5182 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Pathogenesis and research progress of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Manuscript Source	Invited Manuscript
All Author List	Guan-Yue Shan, Hui Wan, Yu-Xin Zhang, Jun-Ya Cheng, Duan-Rui Qiao, Yi-Ying Liu, Wen-Na Shi and Hai-Jun Li
ORCID	Author(s) ORCID Number Guan-Yue Shan http://orcid.org/0000-0002-3380-9418 Duan-Rui Qiao http://orcid.org/0000-0001-6875-2143 Hai-Jun Li http://orcid.org/0000-0002-2515-3076
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81970529 National Natural Science Foundation of China 82202414 Natural Science Foundation of Jilin Province 20230508074RC Natural Science Foundation of Jilin Province YDZJ202401218ZYTS
Corresponding Author	Hai-Jun Li, MD, PhD, Associate Professor, Institute of Liver Diseases, Institute of Translational Medicine, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130061, Jilin Province, China. hjli2012@jlu.edu.cn
Key Words	NASH; hepatic steatosis; Sex hormone metabolism; the treatment for NASH
Core Tip	In this study, the modified Xiaoyao San (MXS) formula was found can alleviated inflammation and hepatic steatosis in nonalcoholic steatohepatitis (NASH) by suppressing male hormone metabolism and modulating inflammation/Lipid metabolism-related signaling and factors. It suggested that the regulation of sex hormone metabolism and associated signaling could be new avenues for mechanistic research on NASH and for early diagnosis and treatment. This study offers substantial evidence for the therapeutic potential of MXS in NASH and makes a valuable contribution to the development of new drugs for this condition.
Publish Date	2024-10-21 07:03
Citation	<p>Shan GY, Wan H, Zhang YX, Cheng JY, Qiao DR, Liu YY, Shi WN, Li HJ. Pathogenesis and research progress of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. <i>World J Hepatol</i> 2024; 16(10): 1142-1150</p>
URL	https://www.wjgnet.com/1948-5182/full/v16/i10/1142.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i10.1142

Full Article (PDF)	WJH-16-1142-with-cover.pdf
Manuscript File	99338_Auto_Edited_034509.docx
Answering Reviewers	99338-answering-reviewers.pdf
Audio Core Tip	99338-audio.aac
Conflict-of-Interest Disclosure Form	99338-conflict-of-interest-statement.pdf
Copyright License Agreement	99338-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99338-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	99338-non-native-speakers.pdf
Peer-review Report	99338-peer-reviews.pdf
Scientific Misconduct Check	99338-scientific-misconduct-check.png
Scientific Editor Work List	99338-scientific-editor-work-list.pdf
CrossCheck Report	99338-crosscheck-report.pdf
CrossCheck Report	99338-crosscheck-report.png