Publication Name	World Journal of Gastroenterology
Manuscript ID	9936
Country	Poland

Received	2014-03-05 08:43
Peer-Review Started	2014-03-05 10:03
To Make the First Decision	2014-04-02 19:24
Return for Revision	2014-04-14 08:14
Revised	2014-04-15 18:13
Second Decision	2014-08-28 09:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-08-28 10:22
Articles in Press	2014-08-28 10:55
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-09-02 00:33
Typeset the Manuscript	2014-11-25 18:08
Publish the Manuscript Online	2014-12-10 15:52

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Hormonal protection in acute pancreatitis by ghrelin, leptin and melatonin
Manuscript Source	Invited Manuscript
All Author List	Jolanta Jaworek and Stanisław Jan Konturek
Funding Agency and Grant Number
Corresponding Author	Jolanta Jaworek, MD, PhD, Department of Medical Physiology, Faculty of Health Sciences, Jagiellonian University Collegium Medicum, Michałowskiego str. 12, 31-125 Kraków, Poland. mpjawore@cyf-kr.edu.pl
Key Words	Acute pancreatitis; Protection; Ghrelin; Leptin; Melatonin
Core Tip	The pathogenesis of acute pancreatitis is not clear and treatment of this disease is unspecific. Since the severe form of acute pancreatitis often leads to death or to pancreatic insufficiency, the understanding of the mechanisms involved in pancreatic protection appears to be an important problem. Experimental data have shown that pancreatitis severity could be attenuated by various hormones. Herein, we review the results of our research studies and others, as well as data from clinical observations concerning the protective effects of ghrelin, leptin and melatonin on acute pancreatitis. We also present the hypothetical mechanisms responsible for the beneficial influence of these substances on pancreatic inflammation.
Publish Date	2014-12-10 15:52
Citation	Jaworek J, Konturek SJ. Hormonal protection in acute pancreatitis by ghrelin, leptin and melatonin. World J Gastroenterol 2014; 20(45): 16902-16912
URL	http://www.wjgnet.com/1007-9327/full/v20/i45/16902.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i45.16902

Full Article (PDF)	WJG-20-16902.pdf
Full Article (Word)	WJG-20-16902.doc
Manuscript File	9936-Review.doc
Answering Reviewers	9936-Answering reviewers.pdf
Copyright License Agreement	9936-Copyright assignment.pdf
Peer-review Report	9936-Peer review.pdf
Scientific Misconduct Check	9936-CorssCheck.jpg
Scientific Editor Work List	9936-Scientific editor work list.pdf