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Articles Published Processes
6/16/2025 10:38:20 AM | Browse: 8 | Download: 143
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Received |
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2024-08-22 07:45 |
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Peer-Review Started |
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2024-07-21 16:36 |
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To Make the First Decision |
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Return for Revision |
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2024-12-05 06:17 |
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Revised |
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2024-12-15 15:14 |
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Second Decision |
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2025-03-13 02:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-13 07:17 |
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Articles in Press |
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2025-03-13 07:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-06 08:00 |
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Publish the Manuscript Online |
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2025-06-16 10:38 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Exploring small intestinal bacterial overgrowth in functional upper gastrointestinal disorder: A comprehensive case-control study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bhaswati C Acharyya and Meghdeep Mukhopadhyay |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bhaswati C Acharyya, MD, Professor, Department of Pediatric Gastroenterology and Hepatology, Institute of Child Health, 11, Dr Biresh Guha Street, Kolkata 700017, West Bengal, India. bacharyya21@gmail.com |
| Key Words |
Small intestinal; Bacterial overgrowth; Hydrogen breath test; Functional gastrointestinal; Proton pump inhibitor |
| Core Tip |
Small intestinal bacterial overgrowth (SIBO) is defined as an increased number of non-pathogenic bacteria over 105 organisms/mL of small intestinal content. The most common predisposing factors include, among others, gut motility disorders and chronic use of proton pump inhibitors. SIBO is suspected and excluded frequently in functional gastrointestinal (GI) disorders like functional abdominal pain, irritable bowel syndrome, functional dyspepsia, or functional defecation disorder. However, the extent of SIBO in functional GI disorders, which mainly manifest with upper gastrointestinal symptoms such as nausea, vomiting, epigastric pain, belching, dyspepsia, etc, has not been documented earlier. This study uniquely divides the proton pump inhibitor naive children into two groups: One with demonstrable endoscopic lesions (control) and the other without the endoscopic lesions (cases) and compares the prevalence of SIBO between these two groups instead of comparing the cases with healthy children without any symptoms. The result documented a significantly increased number of SIBO in the children with normal endoscopic evaluation. Henceforth, this study documents a need to evaluate the children with functional upper GI symptoms for SIBO. |
| Publish Date |
2025-06-16 10:38 |
| Citation |
<p>Acharyya BC, Mukhopadhyay M. Exploring small intestinal bacterial overgrowth in functional upper gastrointestinal disorder: A comprehensive case-control study. <i>World J Clin Pediatr</i> 2025; 14(3): 99395</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i3/99395.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i3.99395 |
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