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11/12/2024 12:23:34 PM | Browse: 246 | Download: 1012
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 99402
Country Peru
Received
2024-07-22 00:26
Peer-Review Started
2024-07-22 00:26
First Decision by Editorial Office Director
2024-08-17 19:16
Return for Revision
2024-08-17 19:16
Revised
2024-08-31 10:45
Publication Fee Transferred
2024-09-25 14:34
Second Decision by Editor
2024-09-19 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-09-19 08:17
Articles in Press
2024-09-19 08:17
Edit the Manuscript by Language Editor
2024-10-11 10:52
Typeset the Manuscript
2024-10-16 03:17
Publish the Manuscript Online
2024-11-12 12:23
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Temozolomide and capecitabine regimen as first-line treatment in advanced gastroenteropancreatic neuroendocrine tumors at a Latin American reference center
Manuscript Source Unsolicited Manuscript
All Author List Wagner Eduardo Cruz-Diaz, Victor Paitan, Jersinho Medina, Raymundo Flores, Juan Haro-Varas, Raul Mantilla and Victor Castro-Oliden
ORCID
Author(s) ORCID Number
Wagner Eduardo Cruz-Diaz http://orcid.org/0009-0006-8138-4430
Victor Paitan http://orcid.org/0000-0003-1120-4335
Juan Haro-Varas http://orcid.org/0000-0003-0678-585X
Raul Mantilla http://orcid.org/0000-0001-6010-1741
Victor Castro-Oliden http://orcid.org/0000-0003-2828-7325
Funding Agency and Grant Number
Corresponding Author Wagner Eduardo Cruz-Diaz, MD, Staff Physician, Department of Oncology, Instituto Nacional de Enfermedades Neoplasicas, Avenue Angamos Este 2520, Surquillo, Lima 15038, Peru. wagner.cruz@upch.pe
Key Words Well-differentiated; Gastroenteropancreatic neuroendocrine tumors; Capecitabine; Temozolomide; Retrospective study; Treatment; Chemotherapy
Core Tip In this study, patients diagnosed with advanced gastroenteropancreatic neuroendocrine tumors who were treated with the temozolomide and capecitabine regimen exhibited a median overall survival of 49 months, with 42% surviving at 60 months. The regimen was well-tolerated, and most patients experienced stable disease. These findings suggest that this treatment could be viable in settings where standard therapies are unavailable or inaccessible, though further prospective studies are needed for confirmation.
Publish Date 2024-11-12 12:23
Citation

Cruz-Diaz WE, Paitan V, Medina J, Flores R, Haro-Varas J, Mantilla R, Castro-Oliden V. Temozolomide and capecitabine regimen as first-line treatment in advanced gastroenteropancreatic neuroendocrine tumors at a Latin American reference center. World J Gastrointest Oncol 2024; 16(12): 4675-4684

URL https://www.wjgnet.com/1948-5204/full/v16/i12/4675.htm
DOI https://dx.doi.org/10.4251/wjgo.v16.i12.4675
Full Article (PDF) WJGO-16-4675-with-cover.pdf