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12/26/2024 3:04:22 AM | Browse: 307 | Download: 1017
Publication Name World Journal of Experimental Medicine
Manuscript ID 99516
Country Egypt
Received
2024-07-24 09:26
Peer-Review Started
2024-07-24 09:26
First Decision by Editorial Office Director
2024-09-02 23:17
Return for Revision
2024-09-02 23:17
Revised
2024-09-17 10:23
Publication Fee Transferred
Second Decision by Editor
2024-10-22 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-10-22 13:50
Articles in Press
2024-10-22 13:50
Edit the Manuscript by Language Editor
2024-10-30 22:45
Typeset the Manuscript
2024-11-06 07:01
Publish the Manuscript Online
2024-12-26 03:04
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Prevalence of RUNX1 gene alterations in de novo adult acute myeloid leukemia
Manuscript Source Invited Manuscript
All Author List Hoda M Abd El-Ghany, Mona S El Ashry, Mona S Abdellateif, Ahmed Rabea, Nada Sultan and Omnia Y Abd El Dayem
ORCID
Author(s) ORCID Number
Mona S Abdellateif http://orcid.org/0000-0002-5510-4435
Funding Agency and Grant Number
Corresponding Author Mona S Abdellateif, MD, PhD, Professor, Department of Cancer Biology, National Cancer Institute, Cairo University, 1 Fom Elkhaligue, cairo 11976, Al Qāhirah, Egypt. mona.sayed@nci.cu.edu.eg
Key Words Acute myeloid leukemia; Deletion; Disease-free survival; Fluorescence in-situ hybridization; Karyotyping; RUNX1
Core Tip In the current study, we tried to characterize RUNX1 gene rearrangements and copy number variations in newly diagnosed adult acute myeloid leukemia patients, with emphasis on the impact of clinical, and laboratory features on the outcome. RUNX1 abnormalities were mutually exclusive of NPM1 mutations. RUNX1 abnormalities affected neither patients’ response to treatment nor overall survival.
Publish Date 2024-12-26 03:04
Citation

Abd El-Ghany HM, El Ashry MS, Abdellateif MS, Rabea A, Sultan N, Abd El Dayem OY. Prevalence of RUNX1 gene alterations in de novo adult acute myeloid leukemia. World J Exp Med 2025; 15(1): 99516

URL https://www.wjgnet.com/2220-315x/full/v15/i1/99516.htm
DOI https://dx.doi.org/10.5493/wjem.v15.i1.99516
Full Article (PDF) WJEM-15-99516-with-cover.pdf