Publication Name	World Journal of Methodology
Manuscript ID	99580
Country	India

Received	2024-08-23 03:27
Peer-Review Started	2024-07-25 09:34
To Make the First Decision
Return for Revision	2024-09-29 13:25
Revised	2024-10-11 09:34
Second Decision	2024-11-04 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-04 10:04
Articles in Press	2024-11-04 10:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-06 10:15
Publish the Manuscript Online	2024-11-27 10:57

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Basic Study
Article Title	Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy
Manuscript Source	Invited Manuscript
All Author List	Vandana Tayal, Akash Mandal, Ijasul Haque M, Akhilesh Mishra, Bhupinder S Kalra and Vandana Roy
ORCID	Author(s) ORCID Number Vandana Tayal http://orcid.org/0000-0002-0687-8346 Ijasul Haque M http://orcid.org/0000-0001-9378-6257
Funding Agency and Grant Number
Corresponding Author	Vandana Tayal, MD, Professor, Department of Pharmacology, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi 110002, India. vandana_tayal@yahoo.com
Key Words	Antiepileptic; Anticonvulsant; Statins; Rosuvastatin; Maximal electroshock seizure; Pentylenetetrazol
Core Tip	Many patients do not benefit from the available antiepileptics. Statins are known for their pleiotropic effects, which include neuroprotective properties. We investigated whether rosuvastatin, a potent statin, has anticonvulsant properties on its own or if it potentiates the effects of standard anticonvulsants. The study used maximal electroshock and pentylenetetrazol seizure models in albino mouse We observed that rosuvastatin potentiated some of the anticonvulsant effects of the standard antiepileptics carbamazepine and valproate.
Publish Date	2024-11-27 10:57
Citation	<p>Tayal V, Mandal A, Haque M I, Mishra A, Kalra BS, Roy V. Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy. <i>World J Methodol</i> 2025; 15(2): 99580</p>
URL	https://www.wjgnet.com/2222-0682/full/v15/i2/99580.htm
DOI	https://dx.doi.org/10.5662/wjm.v15.i2.99580

Full Article (PDF)	WJM-15-99580-with-cover.pdf
The ARRIVE Guidelines	99580-The-ARRIVE-Guidelines.pdf
Manuscript File	99580_Auto_Edited_014438.docx
Answering Reviewers	99580-answering-reviewers.pdf
Audio Core Tip	99580-audio.mp3
Biostatistics Review Certificate	99580-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	99580-conflict-of-interest-statement.pdf
Copyright License Agreement	99580-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	99580-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	99580-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	99580-non-native-speakers.pdf
Peer-review Report	99580-peer-reviews.pdf
Scientific Misconduct Check	99580-scientific-misconduct-check.png
Scientific Editor Work List	99580-scientific-editor-work-list.pdf
CrossCheck Report	99580-crosscheck-report.pdf