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Articles Published Processes
5/26/2025 9:15:10 AM | Browse: 22 | Download: 54
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Received |
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2024-07-26 12:37 |
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Peer-Review Started |
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2024-07-26 12:37 |
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To Make the First Decision |
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Return for Revision |
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2024-11-18 08:56 |
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Revised |
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2024-12-27 10:15 |
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Second Decision |
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2025-04-11 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-11 07:38 |
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Articles in Press |
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2025-04-11 07:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-16 07:38 |
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Publish the Manuscript Online |
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2025-05-26 09:15 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Editorial |
| Article Title |
Are mesenchymal stem/stromal cells a novel avenue for the treatment of non-alcoholic fatty liver disease?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Milton Artur Ruiz, Roberto Luiz R Kaiser Junior, Gabriel Piron-Ruiz and Luiz Gustavo de Quadros |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Milton Artur Ruiz, Emeritus Professor, MD, PhD, Department of Bone Marrow Transplantation, Associação Portuguesa de Beneficência, Rua Catarina Nucci Parise 760, São José do Rio Preto 15090 470, São Paulo, Brazil. milruiz@yahoo.com.br |
| Key Words |
Non-alcoholic fatty liver disease; Mesenchymal stem/stromal cells; Stem cell therapy; Severe liver disease; Non-alcoholic steatohepatitis; Cirrhosis |
| Core Tip |
As non-alcoholic fatty liver disease affects 30% of the world’s population and it should be considered a public health problem. Mesenchymal stem/stromal cells (MSCs) are a type of cell with a high degree of differentiation, immunomodulatory and regenerative potential, which qualifies them for the treatment of inflammatory, autoimmune and immune-mediated diseases. MSCs could be the basis for developing drugs to treat diseases that currently have no definitive or curative treatment. MSCs have the potential to transform into hepatocytes and reduce steatosis and the degree of liver fibrosis. MSCs are promising for the treatment of non-alcoholic fatty liver disease, but there is a need to design clinical trials to obtain robust results for their implementation in medical practice. |
| Publish Date |
2025-05-26 09:15 |
| Citation |
<p>Ruiz MA, Kaiser Junior RLR, Piron-Ruiz G, de Quadros LG. Are mesenchymal stem/stromal cells a novel avenue for the treatment of non-alcoholic fatty liver disease? <i>World J Stem Cells</i> 2025; 17(5): 99638</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i5/99638.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i5.99638 |
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