Publication Name	World Journal of Nephrology
Manuscript ID	99643
Country	Pakistan

Received	2024-07-26 16:18
Peer-Review Started	2024-07-26 16:18
To Make the First Decision
Return for Revision	2024-08-18 20:52
Revised	2024-08-26 11:20
Second Decision	2024-09-19 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-19 13:30
Articles in Press	2024-09-19 13:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-25 02:30
Publish the Manuscript Online	2024-11-07 08:48

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Retrospective Cohort Study
Article Title	Adult minimal change disease: Clinicopathologic characteristics, treatment response and outcome at a single center in Pakistan
Manuscript Source	Invited Manuscript
All Author List	Shaheera Shakeel, Rahma Rashid, Nazarul H Jafry and Muhammed Mubarak
ORCID	Author(s) ORCID Number Shaheera Shakeel http://orcid.org/0000-0002-0142-6682 Rahma Rashid http://orcid.org/0000-0002-9332-2644 Nazarul H Jafry http://orcid.org/0000-0003-4800-9920 Muhammed Mubarak http://orcid.org/0000-0001-6120-5884
Funding Agency and Grant Number
Corresponding Author	Muhammed Mubarak, FCPS, Professor, Department of Histopathology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com
Key Words	Minimal change disease; Nephrotic syndrome; Adults; Steroid therapy; Immunosuppression; Clinical outcomes; Pakistan
Core Tip	Minimal change disease (MCD) constitutes the third most common cause of nephrotic syndrome in adults. The information is scanty on the clinicopathological features, treatment responses, and long-term outcomes of MCD in adults, particularly from developing countries. This study revealed that MCD in adults shows a favorable response to steroid therapy, with a majority achieving remission. However, relapses are common, necessitating second-line immunosuppressive treatments in some cases. The study highlights the need for standardized treatment guidelines for adult MCD to optimize outcomes.
Publish Date	2024-11-07 08:48
Citation	<p>Shakeel S, Rashid R, Jafry NH, Mubarak M. Adult minimal change disease: Clinicopathologic characteristics, treatment response and outcome at a single center in Pakistan. <i>World J Nephrol</i> 2024; 13(4): 99643</p>
URL	https://www.wjgnet.com/2220-6124/full/v13/i4/99643.htm
DOI	https://dx.doi.org/10.5527/wjn.v13.i4.99643

Full Article (PDF)	WJN-13-99643-with-cover.pdf
STROBE Statement	99643-STROBE-statement.pdf
Manuscript File	99643_Auto_Edited_022430.docx
Answering Reviewers	99643-answering-reviewers.pdf
Audio Core Tip	99643-audio.opus
Biostatistics Review Certificate	99643-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	99643-conflict-of-interest-statement.pdf
Copyright License Agreement	99643-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	99643-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	99643-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	99643-non-native-speakers.pdf
Peer-review Report	99643-peer-reviews.pdf
Scientific Misconduct Check	99643-scientific-misconduct-check.png
Scientific Editor Work List	99643-scientific-editor-work-list.pdf
CrossCheck Report	99643-crosscheck-report.png
CrossCheck Report	99643-crosscheck-report.pdf