| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Observational Study |
| Article Title |
Risk of COVID-19 infection among frontline healthcare workers during the COVID-19 pandemic
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Kundavaram Paul Prabhakar Abhilash, Mathew Varghese Nellimootil, Binila Chacko, Darpanarayan Hazra, Victor Coelho, John Emmanuel Jesudasan, Karthik Gunasekaran, Lovely Thomas, More Atul Ramchandra, Jonathan Melchizedek, Henah Meshack Gunaraj, Mahesh Moorthy and John Victor Peter |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Internal Institutional Research Fund |
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| Corresponding Author |
John Victor Peter, MD, Professor, Department of Medical Intensive Care, Christian Medical College Vellore, Ida Scudder Road, Vellore 632004, Tamil Nādu, India. peterjohnvictor@yahoo.com.au |
| Key Words |
COVID-19 pandemic; Seroprevalence; Healthcare workers; SARS-CoV-2 antibodies; Nucleocapsid antibody; Spike protein antibody |
| Core Tip |
This study tracked clinical infection and seroprevalence to severe acute respiratory syndrome-coronavirus 2 virus during the two waves of the pandemic in India and compared infection risk between health care workers (HCWs) in high-risk (HR) areas (emergency department, critical care) and low-risk (LR) non-clinical areas. The seroprevalence rate of 1.1% at the start of the pandemic increased to 34.1% and 60.1% during the first and second waves respectively. Prior to vaccination, more HCWs in HR areas developed clinical infection. Following vaccination, clinical infection rates and seropositivity were similar in HR and LR groups. About 1/3rd had evidence of subclinical infection. |
| Publish Date |
2025-06-23 07:18 |
| Citation |
<p>Abhilash KPP, Nellimootil MV, Chacko B, Hazra D, Coelho V, Jesudasan JE, Gunasekaran K, Thomas L, Ramchandra MA, Melchizedek J, Gunaraj HM, Moorthy M, Peter JV. Risk of COVID-19 infection among frontline healthcare workers during the COVID-19 pandemic. <i>World J Virol</i> 2025; 14(2): 99663</p> |
| URL |
https://www.wjgnet.com/2220-3249/full/v14/i2/99663.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v14.i2.99663 |
