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1/13/2025 8:26:46 AM | Browse: 36 | Download: 98
Publication Name World Journal of Orthopedics
Manuscript ID 99690
Country India
Received
2024-07-28 07:07
Peer-Review Started
2024-07-28 07:07
To Make the First Decision
Return for Revision
2024-11-18 10:25
Revised
2024-12-07 14:34
Second Decision
2024-12-25 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-12-25 11:02
Articles in Press
2024-12-25 11:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-01-01 00:24
Typeset the Manuscript
2025-01-07 06:16
Publish the Manuscript Online
2025-01-13 08:26
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Systematic Reviews
Article Title Current status of nanofat in the management of knee osteoarthritis: A systematic review
Manuscript Source Invited Manuscript
All Author List Naveen Jeyaraman, Sandeep Shrivastava, VR Ravi, Arulkumar Nallakumarasamy and Madhan Jeyaraman
ORCID
Author(s) ORCID Number
Naveen Jeyaraman http://orcid.org/0000-0002-4362-3326
VR Ravi http://orcid.org/0009-0006-7303-8474
Arulkumar Nallakumarasamy http://orcid.org/0000-0002-2445-2883
Madhan Jeyaraman http://orcid.org/0000-0002-9045-9493
Funding Agency and Grant Number
Corresponding Author Madhan Jeyaraman, Assistant Professor, PhD, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Velappanchavadi, Chennai 600077, Tamil Nadu, India. madhanjeyaraman@gmail.com
Key Words Osteoarthritis; Nanofat; Adipose tissue; Cartilage; Knee
Core Tip The systematic review establishes that nanofat therapy is a promising intervention for osteoarthritis (OA), offering both pain relief and functional improvement, while also maintaining a favorable safety profile. The therapy's underlying mechanisms include the enhancement of chondrocyte proliferation, reduction of inflammation, and promotion of angiogenesis. Despite these promising findings, the study underscores the need for additional research, particularly in the form of large-scale randomized controlled trials, to validate the long-term efficacy and safety of nanofat therapy in the management of OA.
Publish Date 2025-01-13 08:26
Citation <p>Jeyaraman N, Shrivastava S, Ravi V, Nallakumarasamy A, Jeyaraman M. Current status of nanofat in the management of knee osteoarthritis: A systematic review. <i>World J Orthop</i> 2025; 16(1): 99690</p>
URL https://www.wjgnet.com/2218-5836/full/v16/i1/99690.htm
DOI https://dx.doi.org/10.5312/wjo.v16.i1.99690
Full Article (PDF) WJO-16-99690-with-cover.pdf
PRISMA 2009 Checklist 99690-PRISMA-2009-Checklist.pdf
Manuscript File 99690_Auto_Edited_081632.docx
Answering Reviewers 99690-answering-reviewers.pdf
Audio Core Tip 99690-audio.opus
Biostatistics Review Certificate 99690-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 99690-conflict-of-interest-statement.pdf
Copyright License Agreement 99690-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 99690-non-native-speakers.pdf
Peer-review Report 99690-peer-reviews.pdf
Scientific Misconduct Check 99690-scientific-misconduct-check.png
Scientific Editor Work List 99690-scientific-editor-work-list.pdf
CrossCheck Report 99690-crosscheck-report.pdf