Publication Name	World Journal of Diabetes
Manuscript ID	99726
Country	China

Received	2024-07-30 02:06
Peer-Review Started	2024-08-09 06:07
To Make the First Decision
Return for Revision	2024-09-07 23:05
Revised	2024-09-19 14:13
Second Decision	2024-10-16 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-16 08:04
Articles in Press	2024-10-16 08:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-29 16:33
Publish the Manuscript Online	2024-11-30 03:48

ISSN	1948-9358 (online)
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Category	Endocrinology & Metabolism
Manuscript Type	Letter to the Editor
Article Title	Intestinal glucagon-like peptide-1: A new regulator of impaired counterregulatory responses to hypoglycemia in type 1 diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Le-Rong Liu, Yuan-Yuan Luo, Pei-Zhu Su, Cong Zhang and Zhao-Tao Li
ORCID	Author(s) ORCID Number Le-Rong Liu http://orcid.org/0000-0001-8379-910X Pei-Zhu Su http://orcid.org/0000-0003-1300-3342 Cong Zhang http://orcid.org/0000-0002-0307-8757
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82400966 Guangdong Basic and Applied Basic Research Foundation 2021A1515111025 Science and Technology Projects in Guangzhou 2024A04J5170
Corresponding Author	Cong Zhang, MD, PhD, Department of Gastroenterology, The First People's Hospital of Foshan, No. 81 Lingnan Avenue North, Foshan 528000, Guangdong Province, China. zhangc57@mail2.sysu.edu.cn
Key Words	Glucagon-like peptide-1; Impaired counterregulation; Type 1 diabetes mellitus; Sympathetic-adrenal reflex; Glucagon
Core Tip	Jin et al reported that excessive intestinal glucagon-like peptide-1 (GLP-1) exacerbates impaired counterregulatory responses in individuals with type 1 diabetes mellitus (T1DM). By elucidating the molecular mechanisms through which GLP-1 disrupts the sympathetic-adrenal reflex and inhibits glucagon secretion, the authors explored the significant role of GLP-1 in counterregulatory failure. Further research is needed to understand the potential impact of GLP-1 and its analogs on counterregulatory responses in T1DM patients and to evaluate their prospects as adjunctive treatments for preventing and treating hypoglycemia in patients with diabetes.
Publish Date	2024-11-30 03:48
Citation	<p>Liu LR, Luo YY, Su PZ, Zhang C, Li ZT. Intestinal glucagon-like peptide-1: A new regulator of impaired counterregulatory responses to hypoglycemia in type 1 diabetes mellitus. <i>World J Diabetes</i> 2025; 16(1): 99726</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i1/99726.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i1.99726

Full Article (PDF)	WJD-16-99726-with-cover.pdf
Manuscript File	99726_Auto_Edited_083826.docx
Answering Reviewers	99726-answering-reviewers.pdf
Audio Core Tip	99726-audio.m4a
Conflict-of-Interest Disclosure Form	99726-conflict-of-interest-statement.pdf
Copyright License Agreement	99726-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99726-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	99726-non-native-speakers.pdf
Peer-review Report	99726-peer-reviews.pdf
Scientific Misconduct Check	99726-scientific-misconduct-check.png
Scientific Editor Work List	99726-scientific-editor-work-list.pdf
CrossCheck Report	99726-crosscheck-report.png
CrossCheck Report	99726-crosscheck-report.pdf