Publication Name	World Journal of Radiology
Manuscript ID	99763
Country	China

Received	2024-07-30 14:32
Peer-Review Started	2024-07-30 14:32
To Make the First Decision
Return for Revision	2024-08-19 14:18
Revised	2024-08-27 13:35
Second Decision	2024-09-10 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-10 09:53
Articles in Press	2024-09-10 09:53
Publication Fee Transferred	2024-09-12 02:22
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-18 00:40
Publish the Manuscript Online	2024-09-27 06:36

ISSN	1949-8470 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pharmacology & Pharmacy
Manuscript Type	Case Report
Article Title	Prolonged course of Paxlovid administration in a centenarian with COVID-19: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Xue Zhang, Juan Tang, Dan Zhu, Chun-Yan Wu, Mei-Lan Liang and Yuan-Tao Huang
ORCID	Author(s) ORCID Number Yi-Xue Zhang http://orcid.org/0009-0003-5565-5012 Yuan-Tao Huang http://orcid.org/0000-0002-6465-7795
Funding Agency and Grant Number
Corresponding Author	Yuan-Tao Huang, Doctor, Chief Doctor, Department of Healthcare, Department of Cardiology Central South University Xiangya School of Medicine Affiliated Haikou Hospital, No. 43 Renmin Avenue, Meilan District, Haikou 570208, Hainan Province, China. hyt951232@163.com
Key Words	COVID-19; Paxlovid; Centenarians; Renal insufficiency; Heart failure; Lung infection; Case report
Core Tip	We report a 103-year-old female with renal insufficiency and a history of hypertension. The patient was treated with two courses of Paxlovid at a full dose for 2 days and a half dose for 3 days. Although she had lung infection and heart failure during the treatment, they all improved after treatment and she was discharged from hospital 40 days after admission. This case suggested that Paxlovid can be applied cautiously in centenarians with coronavirus disease 2019 patients with renal insufficiency, and but the liver and kidney function of the patient should be closely monitored.
Publish Date	2024-09-27 06:36
Citation	<p>Zhang YX, Tang J, Zhu D, Wu CY, Liang ML, Huang YT. Prolonged course of Paxlovid administration in a centenarian with COVID-19: A case report. <i>World J Radiol</i> 2024; 16(9): 489-496</p>
URL	https://www.wjgnet.com/1949-8470/full/v16/i9/489.htm
DOI	https://dx.doi.org/10.4329/wjr.v16.i9.489

Full Article (PDF)	WJR-16-489-with-cover.pdf
CARE Checklist–2016	99763-CARE-Checklist-2016.pdf
Manuscript File	99763_Auto_Edited_030825.docx
Answering Reviewers	99763-answering-reviewers.pdf
Audio Core Tip	99763-audio.m4a
Conflict-of-Interest Disclosure Form	99763-conflict-of-interest-statement.pdf
Copyright License Agreement	99763-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	99763-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	99763-non-native-speakers.pdf
Peer-review Report	99763-peer-reviews.pdf
Scientific Misconduct Check	99763-scientific-misconduct-check.png
Scientific Editor Work List	99763-scientific-editor-work-list.pdf
CrossCheck Report	99763-crosscheck-report.pdf