Publication Name	World Journal of Gastroenterology
Manuscript ID	9984
Country	China

Received	2014-03-07 11:37
Peer-Review Started	2014-03-07 11:48
To Make the First Decision	2014-03-12 12:31
Return for Revision	2014-03-13 08:40
Revised
Second Decision	2014-05-14 09:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 09:45
Articles in Press	2014-05-23 10:41
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-19 23:23
Typeset the Manuscript	2014-05-23 14:14
Publish the Manuscript Online	2014-05-28 11:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	LncRNAs expression signatures of hepatocellular carcinoma revealed by microarray
Manuscript Source	Unsolicited Manuscript
All Author List	Wu-Tao Liu, Xin Lu, Guang-Hua Tang, Jin-Jun Ren, Wen-Jun Liao, Peng-Lei Ge and Jie-Fu Huang
Funding Agency and Grant Number	Funding Agency Grant Number China Medical Board of New York 11-045 National Key Technology Research and Development Program of China BAI06B01
Corresponding Author	Xin Lu, MD, Professor of Surgery, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan, Beijing 100730, China. luxinln@gmail.com
Key Words	Long non-coding RNA; Hepatocellular carcinoma; MALAT1; Expression signature; Microarray
Core Tip	Long non-coding RNAs (lncRNAs) possess prominent and diverse regulatory functions in cancer processes. In this study, the expression profiles of lncRNAs in hepatocellular carcinoma (HCC) were analyzed using a microarray-based method. One hundred and seventy-one lncRNAs were significantly downregulated and 488 were upregulated in HCC tissues. Validation was performed in 29 subjects with HCC using quantitative real-time polymerase chain reaction and the expressions of four lncRNAs were significantly downregulated in HCC, whereas the expression of lncRNA MALAT1 showed no significant difference. The same result was obtained in a subset of patients with hepatitis B virus-related HCC.
Publish Date	2014-05-28 11:45
Citation	Liu WT, Lu X, Tang GH, Ren JJ, Liao WJ, Ge PL, Huang JF. LncRNAs expression signatures of hepatocellular carcinoma revealed by microarray. World J Gastroenterol 2014; 20(20): 6314-6321
URL	http://www.wjgnet.com/1007-9327/full/v20/i20/6314.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i20.6314

Full Article (PDF)	WJG-20-6314.pdf
Full Article (Word)	WJG-20-6314.doc
Manuscript File	9984-Review.doc
Answering Reviewers	9984-Answering reviewers.pdf
Copyright License Agreement	9984-Copyright assignment.pdf
Peer-review Report	9984-Peer review(s).pdf
Scientific Editor Work List	9984-Scientific editor work list.pdf