Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	99920
Country	China

Received	2024-08-02 18:14
Peer-Review Started	2024-08-02 18:14
To Make the First Decision
Return for Revision	2024-09-10 00:59
Revised	2024-09-24 00:57
Second Decision	2024-10-18 01:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-18 09:04
Articles in Press	2024-10-18 09:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-24 06:23
Publish the Manuscript Online	2024-11-12 12:23

ISSN	1948-5204 (online)
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Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	Use of traditional Chinese medicine bezoars and bezoar-containing preparations in hepatocarcinoma
Manuscript Source	Invited Manuscript
All Author List	De-Hui Li, Qian-Er Wen, Rui-Qi Feng, Chang Qiao and Xiao-Tong Tian
ORCID	Author(s) ORCID Number De-Hui Li http://orcid.org/0000-0001-7963-9410
Funding Agency and Grant Number	Funding Agency Grant Number Key Research and Development Projects of Hebei Province 18277731D Natural Science Foundation of Hebei Province H202423105 2023 Government-funded Project of The Outstanding Talents Training Program in Clinical Medicine ZF2023165
Corresponding Author	De-Hui Li, MD, Department of Oncology II, The First Affiliated Hospital of Hebei University of Chinese Medicine (Hebei Province Hospital of Chinese Medicine), Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research, Hebei Industrial Technology Institute for Traditional Chinese Medicine Preparation, No. 389 Zhongshan East Road, Chang’an District, Shijiazhuang 050000, Hebei Province, China. 258289951@qq.com
Key Words	Bezoar; Traditional Chinese medicine; Liver cancer; Immune microenvironment; Network pharmacology
Core Tip	Liver cancer seriously affects the physical and mental health of human beings. traditional Chinese medicine (TCM) is an important part of a comprehensive treatment plan, due to its multi-component and multi-target therapeutic characteristics and its known clinical efficacy. However, its mechanism of action is unclear. As science and technology progress and in-depth research leads to the creation of new drugs, many novel treatments for liver cancer have been developed. The research and development of TCM with anti-tumor effects is a hot spot in clinical treatment. Bezoars and bezoar preparations in TCM are known to regulate the immune microenvironment in liver cancer and inhibit the progression of liver cancer through various mechanisms. Targeting these mechanisms through the development of TCM anti-tumor agents, such as nano-bezoars, is the focus of future research.
Publish Date	2024-11-12 12:23
Citation	<p>Li DH, Wen QE, Feng RQ, Qiao C, Tian XT. Use of traditional Chinese medicine bezoars and bezoar-containing preparations in hepatocarcinoma. <i>World J Gastrointest Oncol</i> 2024; 16(12): 4770-4777</p>
URL	https://www.wjgnet.com/1948-5204/full/v16/i12/4770.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i12.4770

Full Article (PDF)	WJGO-16-4770-with-cover.pdf
Manuscript File	99920_Auto_Edited_151008.docx
Answering Reviewers	99920-answering-reviewers.pdf
Audio Core Tip	99920-audio.m4a
Conflict-of-Interest Disclosure Form	99920-conflict-of-interest-statement.pdf
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Scientific Editor Work List	99920-scientific-editor-work-list.pdf
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