Publication Name	World Journal of Diabetes
Manuscript ID	99928
Country	Brazil

Received	2024-08-04 19:34
Peer-Review Started	2024-08-05 01:14
To Make the First Decision
Return for Revision	2024-10-12 04:05
Revised	2024-10-25 03:54
Second Decision	2024-11-04 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-04 08:07
Articles in Press	2024-11-04 08:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-11-21 08:23
Typeset the Manuscript	2024-11-27 09:05
Publish the Manuscript Online	2024-12-30 09:47

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Letter to the Editor
Article Title	Glucagon-like peptide-1 and impaired counterregulatory responses to hypoglycemia in type 1 diabetes
Manuscript Source	Invited Manuscript
All Author List	Gabriel Reis Rocha and Fabrício Freire de Melo
ORCID	Author(s) ORCID Number Gabriel Reis Rocha http://orcid.org/0000-0002-3090-0726 Fabrício Freire de Melo http://orcid.org/0000-0002-5680-2753
Funding Agency and Grant Number	Funding Agency Grant Number Industrial Technological Initiation Scholarship of National Council for Scientific and Technological Development, CNPq No. 0932204294929829 CNPq Research Productivity Fellow No. 4357511882624145
Corresponding Author	Fabrício Freire de Melo, PhD, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormindo Barros, 58, Quadra 17, Lote 58, Vitória da Conquista 45065-430, Bahia, Brazil. freiremeloufba@gmail.com
Key Words	Glucagon-like peptide 1; Type 1 diabetes mellitus; Counterregulatory hypoglycemic dysfunction; Hypoglycemia unawareness; Glucagon; Sympathoadrenal system
Core Tip	Hypoglycemia is a common and significant phenomenon in diabetes type 1, with recurrent episodes causing progressive dysfunction in glycemic counterregulation and reduced hypoglycemia awareness. The involvement of glucagon-like peptide 1 in this impairment is under investigation, but the pathophysiology is complex and multifactorial, involving various hormones and central receptors. Notwithstanding, studies on glucagon-like peptide 1 receptor agonists in type 1 diabetes mellitus have shown promising benefits and a favorable safety profile.
Publish Date	2024-12-30 09:47
Citation	<p>Rocha GR, de Melo FF. Glucagon-like peptide-1 and impaired counterregulatory responses to hypoglycemia in type 1 diabetes. <i>World J Diabetes</i> 2025; 16(2): 99928</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i2/99928.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i2.99928

Full Article (PDF)	WJD-16-99928-with-cover.pdf
Manuscript File	99928_Auto_Edited_062312.docx
Answering Reviewers	99928-answering-reviewers.pdf
Audio Core Tip	99928-audio.m4a
Conflict-of-Interest Disclosure Form	99928-conflict-of-interest-statement.pdf
Copyright License Agreement	99928-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99928-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	99928-non-native-speakers.pdf
Peer-review Report	99928-peer-reviews.pdf
Scientific Misconduct Check	99928-scientific-misconduct-check.png
Scientific Editor Work List	99928-scientific-editor-work-list.pdf
CrossCheck Report	99928-crosscheck-report.png
CrossCheck Report	99928-crosscheck-report.pdf