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2/21/2025 10:12:49 AM | Browse: 48 | Download: 44
Publication Name World Journal of Transplantation
Manuscript ID 99952
Country Saudi Arabia
Received
2024-08-03 17:58
Peer-Review Started
2024-08-03 17:58
To Make the First Decision
Return for Revision
2024-09-19 21:57
Revised
2024-10-11 22:47
Second Decision
2024-12-03 03:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-12-03 09:19
Articles in Press
2024-12-03 09:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2024-12-10 14:44
Typeset the Manuscript
2024-12-18 08:20
Publish the Manuscript Online
2025-02-21 10:12
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Review
Article Title Donor specific antibodies against human leukocyte antigen-C, human leukocyte antigen-DP, human leukocyte antigen-DQ and its implications in kidney transplantation
Manuscript Source Invited Manuscript
All Author List Muhammad Abdul Mabood Khalil, Nihal Mohammed Sadagah, Ishida Hediki, Jackson Tan and Salem H Al-Qurashi
ORCID
Author(s) ORCID Number
Muhammad Abdul Mabood Khalil http://orcid.org/0000-0003-2378-7339
Nihal Mohammed Sadagah http://orcid.org/0009-0005-1651-0528
Ishida Hediki http://orcid.org/0000-0001-7370-4728
Jackson Tan http://orcid.org/0000-0002-8176-9393
Salem H Al-Qurashi http://orcid.org/0009-0002-9759-2200
Funding Agency and Grant Number
Corresponding Author Muhammad Abdul Mabood Khalil, Center of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Al Kurnaysh Br Road, Al Andalus, Jeddah 23311, Saudi Arabia. doctorkhalil1975@hotmail.com
Key Words Kidney transplantation; Human leukocyte antigen-C; Human leukocyte antigen-DP; Human leukocyte antigen-DQ; Donor specific antibodies; Review
Core Tip Human leukocyte antigen (HLA)-C, HLA-DP, HLA-DQ antigens are capable of initiating alloimmune responses and donor specific antibodies (DSAs), which can cause antibody-mediated rejection (AMR), mixed rejection, chronic AMR and reduced graft survival. Better matching for these antigens could reduce production of DSAs, leading to better graft and patient outcomes. This review will explore the reasons for not typing these antigens in the past, examine evidence for its harmful effects, and propose a way forward that will help clinicians to avoid or minimize the harmful effects of these DSAs.
Publish Date 2025-02-21 10:12
Citation <p>Khalil MAM, Sadagah NM, Hediki I, Tan J, Al-Qurashi SH. Donor specific antibodies against human leukocyte antigen-C, human leukocyte antigen-DP, human leukocyte antigen-DQ and its implications in kidney transplantation. <i>World J Transplant</i> 2025; 15(2): 99952</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i2/99952.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i2.99952
Full Article (PDF) WJT-15-99952-with-cover.pdf
Manuscript File 99952_Auto_Edited_014425.docx
Answering Reviewers 99952-answering-reviewers.pdf
Audio Core Tip 99952-audio.opus
Conflict-of-Interest Disclosure Form 99952-conflict-of-interest-statement.pdf
Copyright License Agreement 99952-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 99952-non-native-speakers.pdf
Peer-review Report 99952-peer-reviews.pdf
Scientific Misconduct Check 99952-scientific-misconduct-check.png
Scientific Editor Work List 99952-scientific-editor-work-list.pdf
CrossCheck Report 99952-crosscheck-report.pdf