Publication Name	World Journal of Gastroenterology
Manuscript ID	9999
Country	China

Received	2014-03-08 09:07
Peer-Review Started	2014-03-08 09:22
To Make the First Decision	2014-04-03 10:35
Return for Revision	2014-04-08 08:22
Revised	2014-04-28 18:39
Second Decision	2014-05-19 15:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-19 15:28
Articles in Press	2014-05-23 10:32
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-28 22:23
Typeset the Manuscript	2014-05-29 18:06
Publish the Manuscript Online	2014-06-16 16:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Influence of adriamycin on changes in Nanog, Oct-4, Sox2, ARID1 and Wnt5b expression in liver cancer stem cells
Manuscript Source	Unsolicited Manuscript
All Author List	Ding Sun, Lei Qin, Yang Xu, Jian-Xia Liu, Li-Ping Tian and Hai-Xin Qian
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81372317
Corresponding Author	Hai-Xin Qian, Chief Physician, Department of General Surgery, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou 215006, Jiangsu Province, China. sunding0126@gmail.com
Key Words	Liver cancer cell; Adriamycin; Stem cell related gene; Western blot; Liver cancer stem cell
Core Tip	This study, comprehensively and systematically reports the gene expression of Nanog, Wnt5b, Oct4, and Sox2 and ARID1A, in two hepatoma cell lines. This was performed to explore the molecular mechanism of the recurrence and metastasis of hepatocellular carcinoma, and to detect accurate markers and targets for stem cell-targeted therapeutic interventions. The results showed that Adriamycin (ADM) increased the death rate of MHCC97-L and HCCLM3 cells, while the growth suppressive effect of ADM was higher in MHCC97-L cells than in HCCLM3 cells.
Publish Date	2014-06-16 16:19
Citation	Sun D, Qin L, Xu Y, Liu JX, Tian LP, Qian HX. Influence of adriamycin on changes in Nanog, Oct-4, Sox2, ARID1 and Wnt5b expression in liver cancer stem cells. World J Gastroenterol 2014; 20(22): 6974-6980
URL	http://www.wjgnet.com/1007-9327/full/v20/i22/6974.htm
DOI	10.3748/wjg.v20.i22.6974

Full Article (PDF)	WJG-20-6974.pdf
Full Article (Word)	WJG-20-6974.doc
Manuscript File	9999-Review.doc
Answering Reviewers	9999-Answering reviewers.pdf
Copyright License Agreement	9999-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9999-Language certificate.pdf
Peer-review Report	9999-Peer review.pdf
Scientific Editor Work List	9999-Scientific editor work list.pdf