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11/10/2014 7:09:00 PM | Browse: 996 | Download: 896
Publication Name World Journal of Gastroenterology
Manuscript ID 10154
Country/Territory Greece
Received
2014-03-16 18:22
Peer-Review Started
2014-03-16 23:38
To Make the First Decision
2014-04-15 20:02
Return for Revision
2014-04-23 19:08
Revised
2014-05-21 00:00
Second Decision
2014-06-17 09:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-17 09:53
Articles in Press
2014-06-17 10:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-10-20 15:46
Publish the Manuscript Online
2014-11-10 19:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Immune-modulating therapy in acute pancreatitis: Fact or fiction
Manuscript Source Invited Manuscript
All Author List Karolina Akinosoglou and Charalambos Gogos
Funding Agency and Grant Number
Corresponding Author Karolina Akinosoglou, MD, Department of Internal Medicine and Infectious Diseases, University General Hospital of Patras, 5th Floor, 26504 Rio, Greece. akin@upatras.gr
Key Words Acute pancreatitis; Immune-modulation; Systemic inflammatory response syndrome; Multiple organ dysfunction syndrome; Endoscopic retrograde cholangiopancreatography
Core Tip Acute pancreatitis is a common entity with significant mortality worldwide. Treatment remains non-specific and mainly supportive, mostly focusing on intensive care. Presence of inflammatory response syndrome during AP has driven recent immune-modulating therapeutic attempts in experimental models, including cytokine, chemokine, immune cell and other inflammatory mediator blockade. Although initial data are promising, translation to clinical routine has been less encouraging. The authors attempt to elucidate whether and to what extent tampering with the immune burst triggered by acute pancreatitis could actually ensure better outcomes, or that remains a farfetched expectation.
Publish Date 2014-11-10 19:10
Citation Akinosoglou K, Gogos C. Immune-modulating therapy in acute pancreatitis: Fact or fiction. World J Gastroenterol 2014; 20(41): 15200-15215
URL http://www.wjgnet.com/1007-9327/full/v20/i41/15200.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i41.15200
Full Article (PDF) WJG-20-15200.pdf
Full Article (Word) WJG-20-15200.doc
Manuscript File 10154-Review.docx
Answering Reviewers 10154-Answering reviewers.pdf
Non-Native Speakers of English Editing Certificate 10154-Language certificate.pdf
Peer-review Report 10154-Peer reviews.pdf
Scientific Misconduct Check 10154-CrossCheck.jpg
Scientific Editor Work List 10154-Scientific editor work list.pdf