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Articles Published Processes
10/16/2014 3:53:00 PM | Browse: 1137 | Download: 1121
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Received |
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2014-04-28 09:05 |
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Peer-Review Started |
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2014-04-29 16:15 |
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To Make the First Decision |
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2014-05-29 18:58 |
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Return for Revision |
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2014-06-06 08:56 |
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Revised |
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2014-06-20 20:12 |
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Second Decision |
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2014-07-16 12:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-07-16 13:11 |
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Articles in Press |
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2014-07-16 17:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-07-25 21:09 |
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Typeset the Manuscript |
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2014-09-23 14:49 |
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Publish the Manuscript Online |
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2014-10-16 15:53 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Meta-Analysis |
Article Title |
Bone marrow-derived mesenchymal stem cell therapy for decompensated liver cirrhosis: A meta-analysis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xing-Nan Pan, Lian-Qiu Zheng and Xiao-Huan Lai |
Funding Agency and Grant Number |
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Corresponding Author |
Xin-Nan Pan, Professor, Clinical Liver Center, 180th Hospital of People’s Liberation Army, FengZe Zone Huayuan Rd No. 180, Quanzhou 362000, Fujian Province, China. xnpancn@163.com |
Key Words |
Decompensated liver cirrhosis; Bone marrow stem cell; Transfusion; Meta-analysis |
Core Tip |
Out of 78 studies identified, five studies were included in the final analysis, which showed that the mean decline in scores for the model for end-stage liver disease was -1.23 [95%CI: -2.45-(-0.01)], -1.87 [95%CI: -3.16-(-0.58)], -2.01 [95%CI: -3.35-(-0.68)] at 2, 4 and 24 wk, respectively. The mean improvement in albumin levels was -0.28, 2.60, 5.28, 4.39 g/L at the end of 8, 16, 24, and 48 wk, respectively. Alanine aminotransferase, total bilirubin levels and prothrombin times improved to some extent. Bone marrow-derived mesenchymal stem cell injections resulted in no serious adverse events or complications. |
Publish Date |
2014-10-16 15:53 |
Citation |
Pan XN, Zheng LQ, Lai XH. Bone marrow-derived mesenchymal stem cell therapy for decompensated liver cirrhosis: A meta-analysis. World J Gastroenterol 2014; 20(38): 14051-14057 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i38/14051.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i38.14051 |
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