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10/16/2014 3:53:00 PM | Browse: 1137 | Download: 1121
Publication Name World Journal of Gastroenterology
Manuscript ID 10960
Country/Territory China
Received
2014-04-28 09:05
Peer-Review Started
2014-04-29 16:15
To Make the First Decision
2014-05-29 18:58
Return for Revision
2014-06-06 08:56
Revised
2014-06-20 20:12
Second Decision
2014-07-16 12:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-07-16 13:11
Articles in Press
2014-07-16 17:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-07-25 21:09
Typeset the Manuscript
2014-09-23 14:49
Publish the Manuscript Online
2014-10-16 15:53
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Bone marrow-derived mesenchymal stem cell therapy for decompensated liver cirrhosis: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Xing-Nan Pan, Lian-Qiu Zheng and Xiao-Huan Lai
Funding Agency and Grant Number
Corresponding Author Xin-Nan Pan, Professor, Clinical Liver Center, 180th Hospital of People’s Liberation Army, FengZe Zone Huayuan Rd No. 180, Quanzhou 362000, Fujian Province, China. xnpancn@163.com
Key Words Decompensated liver cirrhosis; Bone marrow stem cell; Transfusion; Meta-analysis
Core Tip Out of 78 studies identified, five studies were included in the final analysis, which showed that the mean decline in scores for the model for end-stage liver disease was -1.23 [95%CI: -2.45-(-0.01)], -1.87 [95%CI: -3.16-(-0.58)], -2.01 [95%CI: -3.35-(-0.68)] at 2, 4 and 24 wk, respectively. The mean improvement in albumin levels was -0.28, 2.60, 5.28, 4.39 g/L at the end of 8, 16, 24, and 48 wk, respectively. Alanine aminotransferase, total bilirubin levels and prothrombin times improved to some extent. Bone marrow-derived mesenchymal stem cell injections resulted in no serious adverse events or complications.
Publish Date 2014-10-16 15:53
Citation Pan XN, Zheng LQ, Lai XH. Bone marrow-derived mesenchymal stem cell therapy for decompensated liver cirrhosis: A meta-analysis. World J Gastroenterol 2014; 20(38): 14051-14057
URL http://www.wjgnet.com/1007-9327/full/v20/i38/14051.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i38.14051
Full Article (PDF) WJG-20-14051.pdf
Full Article (Word) WJG-20-14051.doc
Manuscript File 10960-Review.doc
Answering Reviewers 10960-Answering reviewers.pdf
Copyright License Agreement 10960-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 10960-Language certificate.pdf
Peer-review Report 10960-Peer reviews.pdf
Scientific Misconduct Check 10960-CrossCheck.jpg
Scientific Editor Work List 10960-Scientific editor work list.pdf