Publication Name	World Journal of Nephrology
Manuscript ID	10998
Country	Argentina

Received	2014-04-29 14:10
Peer-Review Started	2014-04-30 11:47
To Make the First Decision	2014-07-18 12:40
Return for Revision	2014-07-18 14:43
Revised	2014-08-29 09:50
Second Decision	2015-01-29 09:15
Accepted by Journal Editor-in-Chief	2015-01-31 07:06
Accepted by Company Editor-in-Chief	2015-02-09 10:37
Articles in Press	2015-02-09 10:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-07 12:07
Publish the Manuscript Online	2015-05-08 14:17

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Review
Article Title	Renal dopaminergic system: Pathophysiological implications and clinical perspectives
Manuscript Source	Invited Manuscript
All Author List	Marcelo Roberto Choi, Nicolás Martín Kouyoumdzian, Natalia Lucía Rukavina Mikusic, María Cecilia Kravetz, María Inés Rosón, Martín Rodríguez Fermepin and Belisario Enrique Fernández
Funding Agency and Grant Number	Funding Agency Grant Number ANPCYT PICT 2012-1775 Universidad de Buenos Aires UBACYT 20020110200048 Universidad de Buenos Aires 20020130200105BA Sociedad Argentina de Hipertensión Arterial (Stimulus Grant for Reasearch on Hypertension 2014-2015)
Corresponding Author	Marcelo R. Choi MD PhD, Department of Pathophysiology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, CONICET, INFIBIOC, Junín 956, 5° piso, Ciudad Autónoma de Buenos Aires, Argentina 1113. marcelinkchoi@yahoo.com.ar
Key Words	Dopamine; kidney; Na+; K+-ATPase; Sodium; Hypertension; Oxidative stress; D1 receptors; D2 receptors; Renal failure; Edema
Core Tip	Renal dopaminergic system is a local independent natriuretic system necessary to maintain the normal balance of sodium and water, blood pressure and renal redox steady state. Different findings from experimental and clinical studies highlight the participation of renal dopamine in the pathophysiology of renal inflammation, hypertension, diabetic nephropathy and edema formation. Recent findings from experimental and clinical studies allow us to understand the complexity of this system as well as its possible contribution for future therapeutic strategies to prevent renal diseases.
Publish Date	2015-05-08 14:17
Citation	Choi MR, Kouyoumdzian NM, Rukavina Mikusic NL, Kravetz MC, Rosón MI, Rodríguez Fermepin M, Fernández BE. Renal dopaminergic system: Pathophysiological implications and clinical perspectives. World J Nephrol 2015; 4(2): 196-212
URL	http://www.wjgnet.com/2220-6124/full/v4/i2/196.htm
DOI	http://dx.doi.org/10.5527/wjn.v4.i2.196

Full Article (PDF)	WJN-4-196.pdf
Full Article (Word)	WJN-4-196.doc
Manuscript File	10998-Review.doc
Answering Reviewers	10998-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	10998-Conflict-of-interest statement.pdf
Copyright License Agreement	10998-Copyright assignment.pdf
Peer-review Report	10998-Peer review(s).pdf
Journal Editor-in-Chief Review Report	10998-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check	10998-Scientific misconduct check.pdf
Scientific Editor Work List	10998-Scientific editor work list.pdf