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Articles Published Processes
1/18/2015 4:09:00 PM | Browse: 738 | Download: 841
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Received |
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2014-05-12 18:56 |
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Peer-Review Started |
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2014-05-12 20:20 |
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To Make the First Decision |
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2014-06-18 17:26 |
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Return for Revision |
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2014-06-20 20:23 |
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Revised |
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2014-07-04 14:23 |
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Second Decision |
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2014-07-30 10:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2014-07-30 10:21 |
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Articles in Press |
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2014-07-30 10:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-09-02 19:35 |
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Typeset the Manuscript |
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2014-12-31 15:58 |
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Publish the Manuscript Online |
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2015-01-18 16:09 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Observational Study |
Article Title |
miRNA-103: Molecular link between insulin resistance and nonalcoholic fatty liver disease
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Qian Xu, Ying Li, Yong-Fang Shang, Hui-Ling Wang and Min-Xiu Yao |
Funding Agency and Grant Number |
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Corresponding Author |
Dr. Min-Xiu Yao, Department of Endo-crinology, the Second Affiliated Hospital of Medical College of Qingdao University, No. 127 Siliunan road, Qingdao 266042, Shandong Province, China. yaominxiu@medmail.com.cn |
Key Words |
miRNA-103; Insulin resistance; Nonalcoholic fatty liver disease |
Core Tip |
Insulin resistance activates development of nonalcoholic fatty liver disease (NAFLD), however, the molecular mechanism is not fully understood. We determined fasting plasma glucose, fasting insulin, triglyceride (TG) and the levels of miRNA-103 (miR-103) in the serum of patients with NAFLD. We found that higher levels of miR-103 were expressed in the serum of patients with NAFLD. miR-103 was positively correlated with homeostasis model assessment and was used to evaluate basal insulin resistance (HOMA-IR), TG and BMI, respectively. miR-103 was an independent factor for HOMA-IR and a risk factor for NAFLD. We conclude that miR-103 is involved in insulin resistance and NAFLD. |
Publish Date |
2015-01-18 16:09 |
Citation |
Xu Q, Li Y, Shang YF, Wang HL, Yao MX. miRNA-103: Molecular link between insulin resistance and nonalcoholic fatty liver disease. World J Gastroenterol 2015; 21(2): 511-516 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i2/511.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i2.511 |
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