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3/30/2015 5:46:00 PM | Browse: 1078 | Download: 1391
Publication Name World Journal of Gastroenterology
Manuscript ID 11358
Country/Territory China
Received
2014-05-17 11:42
Peer-Review Started
2014-05-17 20:14
To Make the First Decision
2014-06-10 13:30
Return for Revision
2014-06-11 10:24
Revised
2014-06-23 00:00
Second Decision
2014-07-30 10:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-07-30 10:24
Articles in Press
2014-07-30 10:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-08-25 23:47
Typeset the Manuscript
2015-03-13 16:13
Publish the Manuscript Online
2015-03-30 14:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Meta-Analysis
Article Title Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy: A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Zhi-Qiang Wang, Long-Qi Chen, Yong Yuan, Wen-Ping Wang, Zhong-Xi Niu, Yu-Shang Yang and Jie Cai
Funding Agency and Grant Number
Corresponding Author Long-Qi Chen, Professor, Department of Thoracic Surgery, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu 610041, Sichuan Province, China. drchenlq@gmail.com
Key Words Neutrophil elastase inhibitor; Esophageal cancer; Esophagectomy; Systematic review; Meta-analysis
Core Tip Radical esophagectomy has been adopted in patients with esophageal carcinoma to improve survival. This technique is highly invasive, leading to excess surgical stress, a perioperative mortality of 3%-10%, and pulmonary disorders account for nearly 30%-60%. Sivelestat sodium hydrate, a specific neutrophil elastase inhibitor, actively protects patients with acute respiratory diseases. The efficacy and safety of sivelestat administered during esophagectomy has produced conflicting results and the conclusions from relevant studies are presented. This meta-analysis revealed that sivelestat is beneficial in patients undergoing esophagectomy, especially in terms of the duration of mechanical ventilation and the incidence of pulmonary complications.
Publish Date 2015-03-30 14:23
Citation Wang ZQ, Chen LQ, Yuan Y, Wang WP, Niu ZX, Yang YS, Cai J. Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy: A systematic review and meta-analysis. World J Gastroenterol 2015; 21(12): 3720-3730
URL http://www.wjgnet.com/1007-9327/full/v21/i12/3720.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i12.3720
Full Article (PDF) WJG-21-3720.pdf
Full Article (Word) WJG-21-3720.doc
Manuscript File 11358-Review.doc
Answering Reviewers 11358-Answering Reviewers.pdf
Copyright License Agreement 11358-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 11358-Language certificate.PDF
Peer-review Report 11358-Peer review.pdf
Scientific Misconduct Check 11358-CorssCheck.jpg
Scientific Editor Work List 11358-Scientific editor work list.pdf