Publication Name	World Journal of Gastroenterology
Manuscript ID	11393
Country	China

Received	2014-05-19 20:10
Peer-Review Started	2014-05-20 18:04
To Make the First Decision	2014-06-27 17:36
Return for Revision	2014-07-07 10:35
Revised	2014-08-04 20:48
Second Decision	2014-11-11 10:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-11-11 10:21
Articles in Press	2014-11-11 10:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-12-07 21:00
Typeset the Manuscript	2015-01-06 10:43
Publish the Manuscript Online	2015-01-18 16:09

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Prophylaxis against hepatitis B virus recurrence after liver transplantation: A registry study
Manuscript Source	Unsolicited Manuscript
All Author List	Shu Shen, Li Jiang, Guang-Qin Xiao, Lu-Nan Yan, Jia-Yin Yang, Tian-Fu Wen, Bo Li, Wen-Tao Wang, Ming-Qing Xu and Yong-Gang Wei
Funding Agency and Grant Number
Corresponding Author	Li Jiang, MD, Liver Transplantation Center, Department of Liver Surgery, West China Hospital of Sichuan University, No. 37 Guoxuexiang Road, Chengdu 610041, Sichuan Province, China. jiangli029@163.com
Key Words	Viral hepatitis; Recurrence; Liver transplantation; Hepatitis B immunoglobulin; Nucleos(t)ide analogue
Core Tip	Little is known about which protocol has the optimal prophylactic effects against hepatitis B virus (HBV) recurrence. In this study, we used data from the China Liver Transplant Registry database to evaluate the long-term prophylactic efficacy of hepatitis B immunoglobulin (HBIG) in combination with different nucleos(t)ide analogues and determine the risk factors for HBV recurrence. This nationwide multicenter study demonstrated that low-dose intramuscular HBIG in combination with a nucleos(t)ide analogue provides effective prophylaxis against recurrent HBV infection posttransplantation at approximately 5% of the cost of conventional high-dose intravenous HBIG regimens. Among them, low-dose intramuscular HBIG combined with entecavir has better prophylactic efficacy than the combination of low-dose intramuscular HBIG and lamivudine.
Publish Date	2015-01-18 16:09
Citation	Shen S, Jiang L, Xiao GQ, Yan LN, Yang JY, Wen TF, Li B, Wang WT, Xu MQ, Wei YG. Prophylaxis against hepatitis B virus recurrence after liver transplantation: A registry study. World J Gastroenterol 2015; 21(2): 584-592
URL	http://www.wjgnet.com/1007-9327/full/v21/i2/584.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i2.584

Full Article (PDF)	WJG-21-584.pdf
Full Article (Word)	WJG-21-584.doc
Manuscript File	11393-Review.doc
Answering Reviewers	11393-Answering reviewers.pdf
Copyright License Agreement	11393-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11393-Language certificate.pdf
Peer-review Report	11393-Peer reviews.pdf
Scientific Misconduct Check	11393-CrossCheck.jpg
Scientific Editor Work List	11393-Scientific editor work list.pdf