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1/18/2015 4:09:00 PM | Browse: 653 | Download: 750
Publication Name World Journal of Gastroenterology
Manuscript ID 11460
Country/Territory China
Received
2014-05-22 09:51
Peer-Review Started
2014-05-22 13:43
To Make the First Decision
2014-06-18 17:16
Return for Revision
2014-06-20 10:19
Revised
2014-07-03 17:16
Second Decision
2014-07-25 09:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-07-25 09:38
Articles in Press
2014-07-25 09:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-08-15 16:19
Typeset the Manuscript
2014-12-29 21:05
Publish the Manuscript Online
2015-01-18 16:09
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Clinical Trials Study
Article Title Response-guided treatment of cirrhotic chronic hepatitis B patients: Multicenter prospective study
Manuscript Source Unsolicited Manuscript
All Author List Er-Li Gu, Yi-Qi Yu, Jia-Li Wang, Yan-Yan Ji, Xiu-Yun Ma, Qing Xie, Hong-Ying Pan, Shan-Min Wu, Jun Li, Cheng-Wei Chen, Xiao-Wei Xu, Yue-Er Wang, Guang-Bi Yao, Hong Wang and Wen-Hong Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
Key Medical Specialties Fund of Shanghai Municipal Health Bureau 05II 011 2-1(partially)
GlaxoSmithKline (China) Investment Co, Ltd 110353
Corresponding author Hong Wang, MD, Department of Gastroenterology and Hepatology, Jing’an District Central Hospital, Jing’an Branch of Huashan Hospital, Fudan University, No. 259 Xikang Road, Shanghai 200040, China. wanghongjzx@aliyun.com
Keywords Hepatitis B; Cirrhosis; Adefovir dipivoxil; Lamivudine; Response-guided therapy
Core Tip We conducted this prospective cohort study to explore an optimized strategy of adding adefovir (ADV) and lamivudine (LAM) at different time points according to the early virological response, and to observe its association with long-term treatment outcomes in cirrhotic hepatitis B (CHB) patients with compensated cirrhosis. We found that optimized response-guided add-on therapy of ADV and LAM maintains long-term suppression of hepatitis B virus DNA and improves liver function in CHB patients with compensated liver cirrhosis.
Publish Date 2015-01-18 16:09
Citation Gu EL, Yu YQ, Wang JL, Ji YY, Ma XY, Xie Q, Pan HY, Wu SM, Li J, Chen CW, Xu XW, Wang YE, Yao GB, Wang H, Zhang WH. Response-guided treatment of cirrhotic chronic hepatitis B patients: Multicenter prospective study. World J Gastroenterol 2015; 21(2): 653-660
Url http://www.wjgnet.com/1007-9327/full/v21/i2/653.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i2.653
Full Article (PDF) WJG-21-653.pdf
Full Article (Word) WJG-21-653.doc
Manuscript File 11460-Review.doc
Answering Reviewers 11460-Answering reviewers.pdf
Copyright License Agreement 11460-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 11460-Language certificate.PDF
Peer-review Report 11460-Peer reviews.pdf
Scientific Misconduct Check 11460-CrossCheck.jpg
Scientific Editor Work List 11460-Scientific editor work list.pdf