| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Problem of hepatocellular carcinoma in West Africa
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Nimzing G Ladep, Olufunmilayo A Lesi, Pantong Mark, Maud Lemoine, Charles Onyekwere, Mary Afihene, Mary ME Crossey and Simon D Taylor-Robinson |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fellowships from The London Clinic, London, United Kingdom |
to Dr. Ladep |
| Halley Stewart Foundation, Cambridge, United Kingdom |
to Mary ME Crossey |
|
| Corresponding Author |
Nimzing G Ladep, MBBS, PhD, FWACP, Hepatology Unit, Imperial College London, 10th Floor, QEQM Building, St Mary’s Hospital Campus, South Wharf Road, London W2 1NY, United Kingdom. n.ladep@imperial.ac.uk |
| Key Words |
Liver cancer; West Africa; Aflatoxin; Surveillance; Hepatitis B |
| Core Tip |
It is known that outside the region of East Asia, sub-Saharan Africa has the highest incidence of hepatocellular carcinoma (HCC). Within Africa the West African region remains the focus of significant disease activity. We reviewed the main issues responsible for this pattern. Although intervention efforts, such as primary prevention through hepatitis B vaccination, has led to reductions of chronic hepatitis B infection in some countries such as Gambia and Senegal, there remains a huge gap in secondary prevention, which are responsible for continuing high mortality to incidence ratio of HCC in West Africa. Collaborative clinical care and basic science translational research holds promise towards changing the current trend.
|
| Publish Date |
2014-11-20 19:46 |
| Citation |
Ladep NG, Lesi OA, Mark P, Lemoine M, Onyekwere C, Afihene M, Crossey MME, Taylor-Robinson SD. Problem of hepatocellular carcinoma in West Africa. World J Hepatol 2014; 6(11): 783-792 |
| URL |
http://www.wjgnet.com/1948-5182/full/v6/i11/783.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v6.i11.783 |
