Publication Name	World Journal of Pharmacology
Manuscript ID	12895
Country	Italy

Received	2014-07-29 10:07
Peer-Review Started	2014-07-30 12:04
To Make the First Decision	2014-09-16 10:49
Return for Revision	2014-09-18 11:52
Revised	2014-10-01 20:34
Second Decision	2014-10-29 18:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-10-29 18:57
Articles in Press	2014-10-29 18:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-28 17:54
Publish the Manuscript Online	2014-12-12 11:14

ISSN	2220-3192 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Telomerase activity: An attractive target for cancer therapeutics
Manuscript Source	Invited Manuscript
All Author List	Lucia Picariello, Cecilia Grappone, Simone Polvani and Andrea Galli
Funding Agency and Grant Number
Corresponding Author	Andrea Galli, MD, PhD, Professor, Gastroenterology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Pieraccini n°6, 50139 Florence, Italy. andrea.galli@unifi.it
Key Words	Human telomerase reverse transcriptase; Immunotherapy; Suicide gene therapy; Acycloguanosyl 5’-thymidyltriphosphate; Telomerase inhibition
Core Tip	One of the hallmark of cancer is the replicative immortality of tumor cells guaranteed by telomerase activity that counteracts progressive telomere shortening during cellular replication: this makes telomerase a tumor marker and a target for anticancer drugs. In this review we summarize and update the most recent innovative studies and results on the different strategies that consider telomerase as a target for cancer therapy. In particular, we try to point out the advantages and the potentialities of some innovative approaches, compared to other, equally promising, but that need further investigations.
Publish Date	2014-12-12 11:14
Citation	Picariello L, Grappone C, Polvani S, Galli A. Telomerase activity: An attractive target for cancer therapeutics. World J Pharmacol 2014; 3(4): 86-96
URL	http://www.wjgnet.com/2220-3192/full/v3/i4/86.htm
DOI	http://dx.doi.org/10.5497/wjp.v3.i4.86

Full Article (PDF)	WJP-3-86.pdf
Full Article (Word)	WJP-3-86.doc
Manuscript File	12895-Review.doc
Answering Reviewers	12895-Answering reviewers.pdf
Copyright License Agreement	12895-Copyright assignment.pdf
Peer-review Report	12895-Peer review(s).pdf
Scientific Misconduct Check	12895-CrossCheck.jpg
Scientific Editor Work List	12895-Scientific editor work list.pdf