BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
4/7/2015 6:08:00 PM | Browse: 1122 | Download: 1107
Publication Name World Journal of Gastroenterology
Manuscript ID 13238
Country/Territory South Korea
Received
2014-08-13 18:40
Peer-Review Started
2014-08-13 19:31
To Make the First Decision
2014-09-15 16:15
Return for Revision
2014-09-17 22:31
Revised
2014-10-10 07:26
Second Decision
2014-11-11 10:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-11-11 10:35
Articles in Press
2014-11-11 11:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-03-21 17:22
Publish the Manuscript Online
2015-04-07 17:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Diagnostic value of PIVKA-Ⅱ and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Seung In Seo, Hyoung Su Kim, Won Jin Kim, Woon Geon Shin, Doo Jin Kim, Kyung Ho Kim, Myoung Kuk Jang, Jin Heon Lee, Joo Seop Kim, Hak Yang Kim, Dong Joon Kim, Myung Seok Lee and Choong Kee Park
Funding Agency and Grant Number
Corresponding Author Dr. Hyoung Su Kim, Department of Internal Medicine, Hallym University Medical Center, 445 Gildong, Kangdong-gu, Seoul 134-701, South Korea. hskim@hallym.or.kr
Key Words Hepatitis B virus; Hepatocellular carcinoma; Alpha-fetoprotein; Prothrombin induced by vitamin K absence-Ⅱ
Core Tip Hepatocellular carcinoma (HCC) surveillance is crucial for patients with chronic hepatitis B (CHB). There have been few studies that have compared the levels of prothrombin induced by vitamin K absence-Ⅱ (PIVKA-Ⅱ) and AFP in hepatitis B virus-associated HCC. Serum PIVKA-Ⅱ, at a level of 40 mAU/mL, is a useful tumor marker to distinguish patients with HCC from those with nonmalignant CHB, especially liver cirrhosis (LC). A combination of AFP and PIVKA-Ⅱ could enhance early detection of HCC in patients with CHB. Therefore, serum PIVKA-Ⅱ levels should be measured in combination with serum AFP levels during the follow-up of patients with CHB and particularly those with LC.
Publish Date 2015-04-07 17:13
Citation Seo SI, Kim HS, Kim WJ, Shin WG, Kim DJ, Kim KH, Jang MK, Lee JH, Kim JS, Kim HY, Kim DJ, Lee MS, Park CK. Diagnostic value of PIVKA-Ⅱ and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma. World J Gastroenterol 2015; 21(13): 3928-3935
URL http://www.wjgnet.com/1007-9327/full/v21/i13/3928.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i13.3928
Full Article (PDF) WJG-21-3928.pdf
Full Article (Word) WJG-21-3928.doc
Manuscript File 13238-Review.doc
Answering Reviewers 13238-Answering reviwerers.pdf
Copyright License Agreement 13238-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 13238-Language certificate.pdf
Peer-review Report 13238-Peer review(s).pdf
Scientific Misconduct Check 13238-CorssCheck.jpg
Scientific Editor Work List 13238-Scientific editor work list.pdf