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2/13/2015 9:30:00 AM | Browse: 489 | Download: 457
Publication Name World Journal of Hepatology
Manuscript ID 13291
Country of Manuscript Source Thailand
Received
2014-08-16 10:50
Peer-Review Started
2014-08-17 20:11
To Make the First Decision
2014-10-14 17:53
Return for Revision
2014-10-17 09:51
Revised
2014-10-27 15:21
Second Decision
2014-11-12 14:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-11-19 11:26
Articles in Press
2014-11-19 11:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-01-27 15:03
Publish the Manuscript Online
2015-02-13 09:30
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Management of patients with hepatitis C infection and renal disease
Manuscript Source Invited Manuscript
All Author List Chalermrat Bunchorntavakul, Monthira Maneerattanaporn and Disaya Chavalitdhamrong
Funding Agency and Grant Number
Corresponding author Chalermrat Bunchorntavakul, MD, Assistant Professor of Medicine, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Rajavithi Hospital, College of Medicine, Rangsit University, Rajavithi Road, Ratchathewi, Bangkok 10400, Thailand. dr.chalermrat@gmail.com
Keywords Hepatitis C; Renal disease; Chronic kidney disease; Dialysis; Interferon; Direct acting antivirals; Cryoglobulinemia
Core Tip Hepatitis C virus (HCV) infection in patients with end-stage renal disease (ESRD) is associated with more rapid liver disease progression and reduced graft and patients’ survival following kidney transplantation. The pharmacokinetics of interferons (IFN), ribavirin (RBV) and sofosbuvir are altered in patients with ESRD. With dose adjustment and careful monitoring, treatment of HCV can be safely utilized and successful in most patients with ESRD. direct acting antiviral (DAA)-based regimens, especially IFN-/RBV-free regimens, are preferred for patients with ESRD and kidney transplantation (KT). However, due to inadequate data on clinical safety and efficacy, DAA-based therapies are not currently recommended in patients with severe renal disease. This review will be focused on evaluations and management of HCV in ESRD, KT recipients and HCV-related renal disease, according to the available treatment options including DAA.
Publish Date 2015-02-13 09:30
Citation Bunchorntavakul C, Maneerattanaporn M, Chavalitdhamrong D. Management of patients with hepatitis C infection and renal disease. World J Hepatol 2015; 7(2): 213-225
Url http://www.wjgnet.com/1948-5182/full/v7/i2/213.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i2.213
Full Article (PDF) WJH-7-213.pdf
Full Article (Word) WJH-7-213.doc
Manuscript File 13291-Review.doc
Answering Reviewers 13291-Answering reviewers.pdf
Copyright License Agreement 13291-Copyright assignment.pdf
Peer-review Report 13291-Peer review(s).pdf
Scientific Misconduct Check 13291-CrossCheck.jpg
Scientific Editor Work List 13291-Scientific editor work list.pdf