Publication Name	World Journal of Diabetes
Manuscript ID	13432
Country	Türkiye

Received	2014-08-23 08:32
Peer-Review Started	2014-08-23 11:42
To Make the First Decision	2014-09-16 11:05
Return for Revision	2014-09-19 12:04
Revised	2014-09-24 13:57
Second Decision	2014-11-21 12:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-12-01 13:59
Articles in Press	2014-12-01 13:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-15 16:06
Publish the Manuscript Online	2015-01-31 14:38

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Diabetes and cardiac autonomic neuropathy: Clinical manifestations, cardiovascular consequences, diagnosis and treatment
Manuscript Source	Invited Manuscript
All Author List	Akif Serhat Balcıoğlu and Haldun Müderrisoğlu
Funding Agency and Grant Number
Corresponding Author	Akif Serhat Balcıoğlu, MD, Medical and Research Center of Alanya, Department of Cardiology, Başkent University, Saray Mahallesi, Yunus Emre Caddesi, No: 1, 07400 Alanya, Antalya, Turkey. serhatbalcioglu@gmail.com
Key Words	Diabetes mellitus; Autonomic neuropathy; Heart rate variability; Cardiac; Cardiovascular reflex tests
Core Tip	Although very frequent, cardiac autonomic neuropathy (CAN) is one of the most commonly overlooked complication of diabetes. Higher incidence of cardiovascular events is encountered with CAN due to its relation with silent myocardial ischemia, arrhythmias, intraoperative cardiovascular instability, orthostatic hypotension and cardiomyopathy. Diabetic patients should be screened for CAN due to the possibility of reversal of cardiovascular denervation in the early stages of the disease. Cardiovascular reflex tests and Holter-derived time- and frequency-domain measurements are frequently used for the diagnosis. Therapeutic approaches are promising and may hinder or reverse the progression of the disease when initiated during the early stages.
Publish Date	2015-01-31 14:38
Citation	Balcıoğlu AS, Müderrisoğlu H. Diabetes and cardiac autonomic neuropathy: Clinical manifestations, cardiovascular consequences, diagnosis and treatment. World J Diabetes 2015; 6(1): 80-91
URL	http://www.wjgnet.com/1948-9358/full/v6/i1/80.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i1.80

Full Article (PDF)	WJD-6-8.pdf
Full Article (Word)	WJD-6-8.doc
Manuscript File	13432-Review.docx
Answering Reviewers	13432-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13432-Conflict-of-interest statement.pdf
Copyright License Agreement	13432-Copyright assignment.pdf
Peer-review Report	13432-Peer review(s).pdf
Scientific Misconduct Check	13432-CrossCheck.jpg
Scientific Editor Work List	13432-Scientific editor work list.pdf