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5/21/2015 2:15:00 PM | Browse: 496 | Download: 459
Publication Name World Journal of Experimental Medicine
Manuscript ID 13487
Country/Territory Netherlands
Received
2014-08-25 17:45
Peer-Review Started
2014-08-26 17:06
To Make the First Decision
2014-10-14 18:11
Return for Revision
2014-10-20 12:12
Revised
2014-10-31 15:12
Second Decision
2015-01-29 09:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-02-09 10:39
Articles in Press
2015-02-09 10:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-04-22 16:05
Publish the Manuscript Online
2015-05-21 14:15
ISSN 2220-315x (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Clinical Trials Study
Article Title Barriers in contribution of human mesenchymal stem cells to murine muscle regeneration
Manuscript Source Invited Manuscript
All Author List Anabel S de la Garza-Rodea, Hester Boersma, Cheryl Dambrot, Antoine AF de Vries, Dirk W van Bekkum and Shoshan Knaän-Shanzer
Funding Agency and Grant Number
Funding Agency Grant Number
Universidad Autonoma de Nuevo Leon, Monterrey, Mexico to AS de la Garza-Rodea
Corresponding author Dr. Shoshan Knaän-Shanzer, Virus and Stem Cell Biology Laboratory, Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, Leiden 2333 ZC, the Netherlands. shoshanknaan@gmail.com
Key Words Skeletal muscle; Muscle regeneration; Muscle implants; Mesenchymal stem cells; Satellite cells
Core Tip The translational relevance of animal models for tissue repair is often ambiguous. We describe here a murine model for the comparison of the regeneration of damaged human and murine skeletal muscle implants and the contribution of human and mouse mesenchymal stem cells (MSCs) to this process. Our findings suggest that murine muscle tissue provides a suboptimal environment for maintenance of human MSC, and that in mouse models their capacity to engage in myoregeneration is underestimated. The added value of the present model is that it permits the dissection of species-specific factors in the microenvironment.
Publish Date 2015-05-21 14:15
Citation de la Garza-Rodea AS, Boersma H, Dambrot C, de Vries AAF, van Bekkum DW, Knaän-Shanzer S. Barriers in contribution of human mesenchymal stem cells to murine muscle regeneration. World J Exp Med 2015; 5(2): 140-153
Url http://www.wjgnet.com/2220-315X/full/v5/i2/140.htm
DOI http://dx.doi.org/10.5493/wjem.v5.i2.140
Full Article (PDF) WJEM-5-140.pdf
Full Article (Word) WJEM-5-140.doc
Manuscript File 13487-Review.doc
Answering Reviewers 13487-Answering reviewers.pdf
Copyright License Agreement 13487-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 13487-Institutional review board statement.pdf
Peer-review Report 13487-Peer-review(s).pdf
Scientific Misconduct Check 13487-Scientific misconduct check.pdf
Scientific Editor Work List 13487-Scientific editor work list.pdf