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12/13/2014 7:02:00 PM | Browse: 1000 | Download: 875
Publication Name World Journal of Diabetes
Manuscript ID 13507
Country/Territory United Kingdom
Received
2014-08-26 09:11
Peer-Review Started
2014-08-26 17:29
To Make the First Decision
2014-09-16 10:55
Return for Revision
2014-09-19 11:59
Revised
2014-10-03 16:40
Second Decision
2014-10-27 16:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-10-27 17:16
Articles in Press
2014-10-27 17:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-11-23 16:08
Publish the Manuscript Online
2014-12-13 19:01
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Review
Article Title Biomarkers in diabetic nephropathy: Present and future
Manuscript Source Invited Manuscript
All Author List Gemma Currie, Gerard McKay and Christian Delles
Funding Agency and Grant Number
Corresponding Author Dr. Gemma Currie, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, G12 8TA Glasgow, United Kingdom. gemma.currie@glasgow.ac.uk
Key Words Diabetes; Nephropathy; Microalbuminuria; Proteinuria; Biomarkers
Core Tip Microalbuminuria (MA) is the earliest and most commonly used clinical index of diabetic nephropathy (DN), however its sensitivity and specificity for early disease detection are limited. Not all patients with MA progress to overt DN, nonalbuminuric DN is common and risk associated with MA is elevated even at levels below currently accepted diagnostic thresholds. There is therefore a need for alternative biomarkers allowing early identification of “at risk” individuals. This review focusses on biomarkers of glomerular and tubular dysfunction, oxidative stress and inflammation that have attracted interest. In addition we review more novel strategies including proteomic, metabolomic and genomic approaches.
Publish Date 2014-12-13 19:01
Citation Currie G, McKay G, Delles C. Biomarkers in diabetic nephropathy: Present and future. World J Diabetes 2014; 5(6): 763-776
URL http://www.wjgnet.com/1948-9358/full/v5/i6/763.htm
DOI http://dx.doi.org/10.4239/wjd.v5.i6.763
Full Article (PDF) WJD-5-763.pdf
Full Article (Word) WJD-5-763.doc
Manuscript File 13507-Review.docx
Answering Reviewers 13507-Answering reviewers.pdf
Copyright License Agreement 13507-Copyright assignment.pdf
Peer-review Report 13507-Peer review(s).pdf
Scientific Misconduct Check 13507-CrossCheck.jpg
Scientific Editor Work List 13507-Scientific editor work list.pdf