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12/13/2014 5:50:00 PM | Browse: 1180 | Download: 1095
Publication Name World Journal of Hepatology
Manuscript ID 13511
Country Egypt
Received
2014-08-26 08:52
Peer-Review Started
2014-08-26 17:44
To Make the First Decision
2014-09-28 12:27
Return for Revision
2014-09-29 15:51
Revised
2014-10-13 08:12
Second Decision
2014-10-29 17:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-10-29 18:49
Articles in Press
2014-10-29 18:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-12-08 17:59
Publish the Manuscript Online
2014-12-13 17:50
ISSN 1948-5182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Minireviews
Article Title Recombinase polymerase amplification as a promising tool in hepatitis C virus diagnosis
Manuscript Source Invited Manuscript
All Author List Hosam Zaghloul and Mahmoud El-shahat
Funding Agency and Grant Number
Corresponding Author Hosam Zaghloul, Professor, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, El Gomhoria Street, Mansoura, Al Daqahliyah 35514-60, Egypt. hosam_z@yahoo.com
Key Words Hepatitis C virus; Nucleic acid testing; Polymerase chain reaction; Point-of-care; Recombinase pol­ymerase amplification
Core Tip Recombinase polymerase amplification (RPA) shows many advantages over both real time polymerase chain reaction and other isothermal Amplification methods. In this review we show the importance of molecular detection methods and how isothermal amplification techniques offer molecular point-of-care diagnosis. RPA shows unique characteristics among isothermal approaches that makes it a promising tool in the molecular diagnosis. Because hepatitis C virus is an endemic viral infection, we suggest that RPA may play an important role and save much time in screening infected individuals and managing the therapeutic course.
Publish Date 2014-12-13 17:50
Citation Zaghloul H, El-shahat M. Recombinase polymerase amplification as a promising tool in hepatitis C virus diagnosis. World J Hepatol 2014; 6(12): 916-922
URL http://www.wjgnet.com/1948-5182/full/v6/i12/916.htm
DOI http://dx.doi.org/10.4254/wjh.v6.i12.916
Full Article (PDF) WJH-6-916.pdf
Full Article (Word) WJH-6-916.doc
Manuscript File 13511-Review.docx
Answering Reviewers 13511-Answering reviewers.pdf
Copyright License Agreement 13511-Copyright assignment.pdf
Peer-review Report 13511-Peer review(s).pdf
Scientific Misconduct Check 13511-CrossCheck.jpg
Scientific Editor Work List 13511-Scientific editor work list.pdf