Publication Name	World Journal of Hepatology
Manuscript ID	13682
Country	India

Received	2014-08-29 09:44
Peer-Review Started	2014-08-30 13:40
To Make the First Decision	2014-10-28 14:28
Return for Revision	2014-11-01 15:00
Revised	2014-11-08 15:09
Second Decision	2014-11-21 08:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-12-01 14:08
Articles in Press	2014-12-01 14:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-20 12:16
Publish the Manuscript Online	2015-03-31 15:58

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Endothelial dysfunction in cirrhosis: Role of inflammation and oxidative stress tive stress
Manuscript Source	Invited Manuscript
All Author List	Balasubramaniyan Vairappan
Funding Agency and Grant Number	Funding Agency Grant Number Department of Biotechnology-Ramalingaswami Fellowship 5 years grant from the Government of India
Corresponding Author	Dr. Balasubramaniyan Vairappan, Assistant Professor, Department of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Dhanvantri Nagar, Gorimedu, Pondicherry 605006, India. balamaniyan@gmail.com
Key Words	Asymmetric dimethylarginine; Endothelial function; Nitric oxide; Portal hypertension; Hepatic cirrhosis; Reactive oxygen species; Inflammation
Core Tip	Endothelial dysfunction (ED) is a key and early relentless event in patients suffering from gastrointestinal bleeding in cirrhosis and involves in response to both vasoactive and vasoconstrictor substances. The one such vasoactive molecule, nitric oxide (NO) plays a prime role in maintaining normal hepatic vascular function and if there any defect in NO availability leads to ED and portal hypertension (PHT) could be of great utility in preventing and curing complications of PHT.
Publish Date	2015-03-31 15:58
Citation	Vairappan B. Endothelial dysfunction in cirrhosis: Role of inflammation and oxidative stress. World J Hepatol 2015; 7(3):443-459
URL	http://www.wjgnet.com/1948-5182/full/v7/i3/443.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i3.443

Full Article (PDF)	WJH-7-443.pdf
Full Article (Word)	WJH-7-443.doc
Manuscript File	13682-Review.docx
Answering Reviewers	13682-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13682-Conflict of interest.pdf
Copyright License Agreement	13682-Copyright assignment.pdf
Peer-review Report	13682-Peer review(s).pdf
Scientific Misconduct Check	13682-CrossCheck.jpg
Scientific Editor Work List	13682-Scientific editor work list.pdf