Publication Name	World Journal of Hepatology
Manuscript ID	13746
Country	United States

Received	2014-08-30 13:04
Peer-Review Started	2014-08-30 17:30
To Make the First Decision	2014-09-28 12:23
Return for Revision	2014-09-30 19:16
Revised	2014-10-10 14:55
Second Decision	2014-11-28 14:51
Accepted by Journal Editor-in-Chief	2014-11-28 15:14
Accepted by Company Editor-in-Chief	2014-12-10 17:18
Articles in Press	2014-12-10 17:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-20 12:15
Publish the Manuscript Online	2015-03-31 15:58

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Topic Highlights
Article Title	Magnetic resonance imaging of the cirrhotic liver: An update
Manuscript Source	Invited Manuscript
All Author List	Agnes Watanabe, Miguel Ramalho, Mamdoh AlObaidy, Hye Jin Kim, Fernanda G Velloni and Richard C Semelka
Funding Agency and Grant Number
Corresponding Author	Richard C Semelka, MD, Department of Radiology, University of North Carolina at Chapel Hill, CB 7510 - 2001 Old Clinic Bldg, Chapel Hill, NC 27599-7510, United States. richsem@med.unc.edu
Key Words	Magnetic resonance imaging; Hepatocellular carcinoma; Hepatic nodules; Liver imaging reporting and data system; Dysplastic nodules; Regenerative nodules
Core Tip	Noninvasive imaging has become the standard for hepatocellular carcinoma (HCC) diagnosis in cirrhotic patients. Typical imaging features of HCC, including increased arterial enhancement and delayed washout, provide very high specificity and acceptable sensitivity in characterizing even very small nodules. Diagnostic limitations apply to detecting hypovascular HCCs and differentiating high-grade dysplastic nodules from early HCCs. New techniques such as diffusion-weighted images, T2*, and hepatocyte-specific magnetic resonance imaging contrast agents, are being currently evaluated, which might improve future detection and characterization of hepatic lesions when combined with the current standard imaging protocols with dynamic imaging.
Publish Date	2015-03-31 15:58
Citation	Watanabe A, Ramalho M, AlObaidy M, Kim HJ, Velloni FG, Semelka RC. Magnetic resonance imaging of the cirrhotic liver: An update. World J Hepatol 2015; 7(3): 468-487
URL	http://www.wjgnet.com/1948-5182/full/v7/i3/468.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i3.468

Full Article (PDF)	WJH-7-468.pdf
Full Article (Word)	WJH-7-468.doc
Manuscript File	13746-Review.docx
Answering Reviewers	13746-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13746-Conflict-of-interest statement.pdf
Copyright License Agreement	13746-Copyright assignment.pdf
Peer-review Report	13746-Peer review(s).pdf
Scientific Misconduct Check	13746-CrossCheck.jpg
Scientific Editor Work List	13746-Scientific editor work list.pdf