| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Oxaliplatin and 5-fluorouracil hepatic infusion with lipiodolized chemoembolization in large hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing-Huan Li, Xiao-Ying Xie, Lan Zhang, Fan Le, Ning-Ling Ge, Li-Xin Li, Yu-Hong Gan, Yi Chen, Ju-Bo Zhang, Tong-Chun Xue, Rong-Xin Chen, Jing-Lin Xia, Bo-Heng Zhang, Sheng-Long Ye, Yan-Hong Wang and Zheng-Gang Ren |
| Funding Agency and Grant Number |
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| Corresponding Author |
Zheng-Gang Ren, PhD, M.D., Key Laboratory of Carcinogenesis and Cancer Invasion, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Ministry of Education, 180 Fenglin Road, Shanghai 200032, China. renzhenggang@hotmail.com |
| Key Words |
Hepatic infusion; Large hepatocellular carcinoma; Oxaliplatin; Transarterial chemoembolization; 5-fluorouracil |
| Core Tip |
Treatment of large unresectable hepatocellular carcinomas (HCCs) with diameters exceeding 10 cm is clinically challenging due to the low response rate and high rate of major complications. In this study, the safety and efficacy of a transarterial chemoembolization modality that included a combination of oxaliplatin and 5-fluorourcil infusion followed by embolization with a mixture of mitomycin and Lipiodol was tested in patients with large HCCs. The results indicate that this modality is a promising treatment for certain patients with large HCCs. |
| Publish Date |
2015-04-07 17:13 |
| Citation |
Li JH, Xie XY, Zhang L, Le F, Ge NL, Li LX, Gan YH, Chen Y, Zhang JB, Xue TC, Chen RX, Xia JL, Zhang BH, Ye SL, Wang YH, Ren ZG. Oxaliplatin and 5-fluorouracil hepatic infusion with lipiodolized chemoembolization in large hepatocellular carcinoma. World J Gastroenterol 2015; 21(13): 3970-3977 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i13/3970.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i13.3970 |
