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12/10/2015 10:35:00 AM | Browse: 486 | Download: 546
Publication Name World Journal of Gastroenterology
Manuscript ID 13835
Country/Territory Japan
Received
2014-09-03 17:42
Peer-Review Started
2014-09-04 16:27
To Make the First Decision
2014-10-14 16:50
Return for Revision
2014-10-17 21:50
Revised
2014-10-22 11:42
Second Decision
2014-11-24 11:56
Accepted by Journal Editor-in-Chief
2014-11-25 01:54
Accepted by Company Editor-in-Chief
2014-12-08 16:36
Articles in Press
2014-12-08 17:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-03-08 17:43
Publish the Manuscript Online
2015-03-19 16:57
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Prospective Study
Article Title Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virus -infected liver
Manuscript Source Invited Manuscript
All Author List Motoyuki Kohjima, Tsuyoshi Yoshimoto, Munechika Enjoji, Nobuyoshi Fukushima, Kunitaka Fukuizumi, Tsukasa Nakamura, Miho Kurokawa, Nao Fujimori, Yusuke Sasaki, Yasushi Shimonaka, Yusuke Murata, Susumu Koyama, Ken Kawabe, Kazuhiro Haraguchi, Yorinobu Sumida, Naohiko Harada, Masaki Kato, Kazuhiro Kotoh and Makoto Nakamuta
Funding Agency and Grant Number
Funding Agency Grant Number
Intractable Disease provided by the Ministry of Health, Labor and Welfare of Japan
Clinical Research from the National Hospital Organization of Japan
Corresponding author Munechika Enjoji, MD, PhD, Health Care Center, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. enjoji@adm.fukuoka-u.ac.jp
Keywords Chronic hepatitis C; Iron-metabolism; Hepcidin; Ferroportin; Interferon
Core Tip The first showing the relationship between expression of iron-metabolism-related genes and response to pegylated-interferon (peg-IFN) and ribavirin (RBV) therapy in patients with chronic hepatitis C. The expression of hepcidin and ferroportin in the liver before therapy was significantly lower in sustained virological response (SVR) patients than non-SVR patients. The expression of hepcidin was positively correlated with that of ferroportin. The variation in hepatic expression profile in iron-metabolism-related genes is important for the response to peg-IFN + RBV treatment.
Publish Date 2015-03-19 16:57
Citation Kohjima M, Yoshimoto T, Enjoji M, Fukushima N, Fukuizumi K, Nakamura T, Kurokawa M, Fujimori N, Sasaki Y, Shimonaka Y, Murata Y, Koyama S, Kawabe K, Haraguchi K, Sumida Y, Harada N, Kato M, Kotoh K, Nakamuta M. Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virus-infected liver. World J Gastroenterol 2015; 21(11): 3291-3299
Url http://www.wjgnet.com/1007-9327/full/v21/i11/3291.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i11.3291
Full Article (PDF) WJG-21-3291.pdf
Full Article (Word) WJG-21-3291.doc
Manuscript File 13835-Review.docx
Answering Reviewers 13835-Answering reviewers.pdf
Copyright License Agreement 13835-Copyright assignment.PDF
Non-Native Speakers of English Editing Certificate 13835-Language certificate.pdf
Peer-review Report 13835-Peer review(s).pdf
Scientific Misconduct Check 13835-CrossCheck.jpg
Scientific Editor Work List 13835-Scientific editor work list.pdf