Publication Name	World Journal of Gastroenterology
Manuscript ID	1395
Country	Italy

Received	2012-12-06 16:22
Peer-Review Started	2012-12-10 10:50
To Make the First Decision	2013-04-16 09:12
Return for Revision	2013-04-18 10:15
Revised	2013-04-22 18:20
Second Decision	2013-05-18 16:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-05-19 23:36
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-03 11:41
Publish the Manuscript Online	2013-07-13 17:01

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Cellular and molecular basis of chronic constipation: Taking the functional/idiopathic label out
Manuscript Source	Invited Manuscript
All Author List	Gabrio Bassotti, Vincenzo Villanacci, Dragos Creƫoiu, Sanda Maria Creƫoiu and Gabriel Becheanu
Funding Agency and Grant Number
Corresponding Author	Gabrio Bassotti, Professor, Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, Piazzale Menghini 1, 06156 Perugia, Italy. gabassot@tin.it
Key Words	Constipation; Enteric glia; Enteric nervous system; Enteric neurons; Interstitial cells of Cajap; Neurogastroenterology
Core Tip	Concerning gut motility, in the last years the basic/clinical interplay between gastroenterology and neurology has become stricter, and many pathologic conditions, among which constipation, related to abnormal gastrointestinal motility are now considered and studied by a neurogastroenterological point of view. However, the fact that these conditions are still labelled as “functional” or “idiopathic” is puzzling. We examined the evidence for taking these labels out from constipation, that should be considered as a true neurenteric dysfunction.
Publish Date	2013-07-13 17:01
Citation	Bassotti G, Villanacci V, Creƫoiu D, Creƫoiu SM, Becheanu G. Cellular and molecular basis of chronic constipation: Taking the functional/idiopathic label out. World J Gastroenterol 2013; 19(26): 4099-4105
URL	http://www.wjgnet.com/1007-9327/full/v19/i26/4099.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i26.4099

Full Article (PDF)	WJG-19-4099.pdf
Manuscript File	1395-Review.doc
Answering Reviewers	1395-Answering reviewers.doc
Copyright License Agreement	1395-Copyright assignment.pdf
Peer-review Report	1395-Peer review(s).pdf
Scientific Editor Work List	1395-Scientific editor work list.doc