Publication Name	World Journal of Diabetes
Manuscript ID	14096
Country

Received	2014-09-18 09:30
Peer-Review Started	2014-09-18 17:19
To Make the First Decision	2015-01-08 14:03
Return for Revision	2015-01-10 20:44
Revised	2015-02-21 04:11
Second Decision	2015-03-09 09:02
Accepted by Journal Editor-in-Chief	2015-03-10 01:53
Accepted by Company Editor-in-Chief	2015-03-18 16:40
Articles in Press	2015-03-18 16:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-24 20:29
Publish the Manuscript Online	2015-06-19 17:20

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Functions of Müller cell-derived vascular endothelial growth factor in diabetic retinopathy
Manuscript Source	Invited Manuscript
All Author List	Juan-Juan Wang, Meili Zhu and Yun-Zheng Le
Funding Agency and Grant Number
Corresponding Author	Yun-Zheng Le, PhD, Department of Medicine Endocrinology, University of Oklahoma Health Sciences Center, 941 S. L. Young Blvd., BSEB 302G, Oklahoma City, OK 73104, United States. yun-le@ouhsc.edu
Key Words	Müller glia; Vascular endothelial growth factor; Protein modification; Inflammation; Blood-retina barriers; Diabetic retinopathy
Core Tip	Diabetic retinopathy is a disorder of blood-retina barriers (BRBs) and neurons. Anti-vascular endothelial growth factor (VEGF) drugs are explored for treating BRB breakdown in the disease. As VEGF is also potentially beneficial, it is essential to understand the cellular and molecular mechanisms of VEGF action in the retina. Discussion is centered on the usefulness of conditional gene targeting mice in dissecting the function of globally expressed VEGF and in identifying significant roles for Müller glia-derived VEGF in diabetes-induced changes in protein expression/modification, inflammation, and BRB lesions and leakage.
Publish Date	2015-06-19 17:20
Citation	Wang JJ, Zhu M, Le YZ. Functions of Müller cell-derived vascular endothelial growth factor in diabetic retinopathy. World J Diabetes 2015; 6(5): 726-733
URL	http://www.wjgnet.com/1948-9358/full/v6/i5/726.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i5.726

Full Article (PDF)	WJD-6-726.pdf
Manuscript File	14096-Review.docx
Answering Reviewers	14096-Answering reviewers.pdf
Copyright License Agreement	14096-Copyright assignment.pdf
Peer-review Report	14096-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	14096-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	14096-Scientific misconduct check.pdf
Scientific Editor Work List	14096-Scientific editor work list.pdf