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Publication Name World Journal of Diabetes
Manuscript ID 14096
Country of Manuscript Source
Received
2014-09-18 09:30
Peer-Review Started
2014-09-18 17:19
To Make the First Decision
2015-01-08 14:03
Return for Revision
2015-01-10 20:44
Revised
2015-02-21 04:11
Second Decision
2015-03-09 09:02
Accepted by Journal Editor-in-Chief
2015-03-10 01:53
Accepted by Company Editor-in-Chief
2015-03-18 16:40
Articles in Press
2015-03-18 16:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-05-24 20:29
Publish the Manuscript Online
2015-06-19 17:20
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Cell Biology
Manuscript type Minireviews
Article Title Functions of Müller cell-derived vascular endothelial growth factor in diabetic retinopathy
Manuscript Source Invited Manuscript
All Author List Juan-Juan Wang, Meili Zhu and Yun-Zheng Le
Funding Agency and Grant Number
Correspondence To Yun-Zheng Le, PhD, Department of Medicine Endocrinology, University of Oklahoma Health Sciences Center, 941 S. L. Young Blvd., BSEB 302G, Oklahoma City, OK 73104, United States. yun-le@ouhsc.edu
Keywords Müller glia; Vascular endothelial growth factor; Protein modification; Inflammation; Blood-retina barriers; Diabetic retinopathy
Core Tip Diabetic retinopathy is a disorder of blood-retina barriers (BRBs) and neurons. Anti-vascular endothelial growth factor (VEGF) drugs are explored for treating BRB breakdown in the disease. As VEGF is also potentially beneficial, it is essential to understand the cellular and molecular mechanisms of VEGF action in the retina. Discussion is centered on the usefulness of conditional gene targeting mice in dissecting the function of globally expressed VEGF and in identifying significant roles for Müller glia-derived VEGF in diabetes-induced changes in protein expression/modification, inflammation, and BRB lesions and leakage.
Publish Date 2015-06-19 17:20
Citation Wang JJ, Zhu M, Le YZ. Functions of Müller cell-derived vascular endothelial growth factor in diabetic retinopathy. World J Diabetes 2015; 6(5): 726-733
Url http://www.wjgnet.com/1948-9358/full/v6/i5/726.htm
DOI http://dx.doi.org/10.4239/wjd.v6.i5.726
Full Article (PDF) WJD-6-726.pdf
Manuscript File 14096-Review.docx
Answering Reviewers 14096-Answering reviewers.pdf
Copyright License Agreement 14096-Copyright assignment.pdf
Peer-review Report 14096-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 14096-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 14096-Scientific misconduct check.pdf
Scientific Editor Work List 14096-Scientific editor work list.pdf