Publication Name	World Journal of Surgical Procedures
Manuscript ID	14288
Country	Taiwan

Received	2014-09-28 09:11
Peer-Review Started	2014-09-28 13:56
To Make the First Decision	2014-11-14 19:35
Return for Revision	2014-11-19 17:28
Revised	2014-12-15 20:17
Second Decision	2015-01-04 16:30
Accepted by Journal Editor-in-Chief	2015-01-06 01:42
Accepted by Company Editor-in-Chief	2015-01-12 14:27
Articles in Press	2015-01-12 14:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-13 17:41
Publish the Manuscript Online	2015-04-02 17:32

ISSN	2219-2832 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Review
Article Title	Impact of circulating tumor cells in colorectal cancer patients undergoing laparoscopic surgery
Manuscript Source	Invited Manuscript
All Author List	Jung-Jyh Hung, Chun-Chi Lin, Shung-Haur Yang and Wei-Shone Chen
Funding Agency and Grant Number
Corresponding Author	Wei-Shone Chen, MD, PhD, Division of Surgery, School of Medicine, National Yang-Ming University, No 201, Sec 2, Shih-Pai Rd 11217, Taipei 112, Taiwan. wschen@vghtpe.gov.tw
Key Words	Laparoscopic surgery; Circulating tumor cell; Prognosis; Colorectal cancer
Core Tip	Although laparoscopic surgery has been widely used for various benign colorectal diseases as well as colorectal cancer, the influence of this procedure on the tumor cell spreading is still unknown. The level of circulating tumor cells (CTCs) in patients with cancer has been reported to be significant prognostic and predictive factors. Whether laparoscopic procedure enhances tumor spreading during operation remains unknown. Significantly less CTC detected during laparoscopic surgery than open surgery for colorectal cancer has been reported. In our previous experience, we have shown that laparoscopic surgery had no significantly deleterious effect on CTCs in colorectal cancer patients.
Publish Date	2015-04-02 17:32
Citation	Hung JJ, Lin CC, Yang SH, Chen WS. Impact of circulating tumor cells in colorectal cancer patients undergoing laparoscopic surgery. World J Surg Proced 2015; 5(1): 75-81
URL	http://www.wjgnet.com/2219-2832/full/v5/i1/75.htm
DOI	http://dx.doi.org/10.5412/wjsp.v5.i1.75

Full Article (PDF)	WJSP-5-75.pdf
Full Article (Word)	WJSP-5-75.doc
Manuscript File	14288-Review.doc
Answering Reviewers	14288-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14288-Conflict-of-interest statement.pdf
Copyright License Agreement	14288-Copyright assignment.pdf
Peer-review Report	14288-Peer review(s).pdf
Scientific Misconduct Check	14288-CrossCheck.jpg
Scientific Editor Work List	14288-Scientific editor work list.pdf