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4/27/2015 4:29:00 PM | Browse: 430 | Download: 804
Publication Name World Journal of Gastroenterology
Manuscript ID 14513
Country/Territory Germany
Received
2014-10-08 18:19
Peer-Review Started
2014-10-09 08:54
To Make the First Decision
2014-11-14 18:58
Return for Revision
2014-11-20 09:09
Revised
2014-12-03 03:17
Second Decision
2014-12-16 15:25
Accepted by Journal Editor-in-Chief
2014-12-18 10:19
Accepted by Company Editor-in-Chief
2014-12-22 17:01
Articles in Press
2014-12-22 17:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-04-14 11:41
Publish the Manuscript Online
2015-04-27 16:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Palliative chemotherapy for gastroesophageal cancer in old and very old patients: A retrospective cohort study at the National Center for Tumor Diseases, Heidelberg
Manuscript Source Unsolicited Manuscript
All Author List Anne Katrin Berger, Stefanie Zschaebitz, Christine Komander, Dirk Jäger and Georg Martin Haag
Funding Agency and Grant Number
Funding Agency Grant Number
Zentrum für Geriatrische Onkologie und Biologie in der Metropolregion Rhein Neckar
Corresponding author Anne Katrin Berger, National Center for Tumor Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany. anne.berger@med.uni-heidelberg.de
Keywords Gastroesophageal cancer; Old patients; Palliative chemotherapy; Toxicity; Eastern Cooperative Oncology Group performance status
Core Tip Data concerning efficacy and safety of palliative chemotherapy for gastroesophageal cancer in patients ≥ 70 years are scarce. Concerns about poor tolerability due to reduced functional status are common, and older patients are at risk for undertreatment. In our analysis of 55 patients ≥ 70 years, the survival times were in good accordance to the results of the landmark phase Ⅲ trials including younger patients. Except for increased polyneuropathy, toxicity rates were also comparable. Initial Eastern Cooperative Oncology Group performance status was a strong prognostic factor for PFS, OS and RS.
Publish Date 2015-04-27 16:22
Citation Berger AK, Zschaebitz S, Komander C, Jäger D, Haag GM. Palliative chemotherapy for gastroesophageal cancer in old and very old patients: A retrospective cohort study at the National Center for Tumor Diseases, Heidelberg. World J Gastroenterol 2015; 21(16): 4911-4918
Url http://www.wjgnet.com/1007-9327/full/v21/i16/4911.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i16.4911
Full Article (PDF) WJG-21-4911.pdf
Full Article (Word) WJG-21-4911.doc
Manuscript File 14513-Review.docx
Answering Reviewers 14513-Answering reviewers.pdf
Biostatistics Review Certificate 14513-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 14513-Conflict-of-interest statement.pdf
Copyright License Agreement 14513-Copyright assignment.pdf
Data Sharing Statement 14513-Data sharing statement.pdf
Institutional Review Board Approval Form or Document 14513-Institutional Review Board statement.pdf
Non-Native Speakers of English Editing Certificate 14513-Language certificate.pdf
Peer-review Report 14513-Peer review(s).pdf
Scientific Misconduct Check 14513-CorssCheck.jpg
Scientific Editor Work List 14513-Scientific editor work list.pdf