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12/10/2015 10:35:00 AM | Browse: 589 | Download: 620
Publication Name World Journal of Gastroenterology
Manuscript ID 14585
Country/Territory Italy
Received
2014-10-14 08:20
Peer-Review Started
2014-10-14 19:54
To Make the First Decision
2014-12-11 20:28
Return for Revision
2014-12-16 15:40
Revised
2014-12-18 00:23
Second Decision
2015-01-30 11:15
Accepted by Journal Editor-in-Chief
2015-02-01 21:46
Accepted by Company Editor-in-Chief
2015-02-05 17:16
Articles in Press
2015-02-05 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-03-08 19:16
Publish the Manuscript Online
2015-03-19 16:57
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry and Molecular Biology
Manuscript Type Minireviews
Article Title Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy
Manuscript Source Invited Manuscript
All Author List Massimo Donadelli, Ilaria Dando, Elisa Dalla Pozza and Marta Palmieri
Funding Agency and Grant Number
Funding Agency Grant Number
Associazione Italiana Ricerca Cancro, Milan, Italy
Fondazione CariPaRo, Padova, Italy
Ministero dell’Istruzione, dell’Università e della Ricerca, Rome, Italy
Corresponding author Massimo Donadelli, PhD, Professor, Department of Life and Reproduction Sciences, Biochemistry Section, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy. massimo.donadelli@univr.it
Keywords Uncoupling protein 2; Target therapy; Reactive oxygen species; Metabolism; Pancreatic cancer
Core Tip The dramatic poor prognosis of pancreatic cancer forces towards the identification of novel efficient therapeutic targets against this neoplasia. Overexpression of uncoupling protein 2 (UCP2) and its functional involvement in cancer development, reactive oxygen species production, and cancer metabolic reprogramming may represent the rationale and the starting point for future drug design projects focused on the identification of specific UCP2 inhibitors as innovative therapeutic tool against pancreatic cancer.
Publish Date 2015-03-19 16:57
Citation Donadelli M, Dando I, Dalla Pozza E, Palmieri M. Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy. World J Gastroenterol 2015; 21(11): 3232-3238
Url http://www.wjgnet.com/1007-9327/full/v21/i11/3232.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i11.3232
Full Article (PDF) WJG-21-3232.pdf
Full Article (Word) WJG-21-3232.doc
Manuscript File 14585-Review.docx
Answering Reviewers 14585-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form Conflict of interest declaration.pdf
Copyright License Agreement 14585-Copyright assignment.pdf
Peer-review Report 14585-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 14585-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check 14585-Scientific misconduct check.pdf
Scientific Editor Work List 14585-Scientific editor work list.pdf