Publication Name	World Journal of Gastroenterology
Manuscript ID	14603
Country	Italy

Received	2014-10-15 08:41
Peer-Review Started	2014-10-15 13:58
To Make the First Decision	2014-11-14 19:06
Return for Revision	2014-11-18 14:01
Revised	2014-12-11 23:24
Second Decision	2015-02-02 10:36
Accepted by Journal Editor-in-Chief	2015-02-02 16:56
Accepted by Company Editor-in-Chief	2015-02-05 17:18
Articles in Press	2015-02-05 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-17 20:56
Publish the Manuscript Online	2015-03-30 14:23

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Lessons from rare tumors: Hepatic lymphoepithelioma-like carcinomas
Manuscript Source	Invited Manuscript
All Author List	Antonio Solinas and Diego F Calvisi
Funding Agency and Grant Number
Corresponding Author	Antonio Solinas, MD, Professor, Department of Biomedical Sciences, University of Sassari, Viale San Pietro 8, 07100 Sassari. Italy. soltoc@uniss.it
Key Words	Lymphoepithelioma; Lymphoepithelioma-like carcinoma; Nasopharyngeal carcinoma; Lymphoepithelioma-like hepatocellular carcinoma; Lymphoepithelioma-like intrahepatic cholangiocarcinoma; Epstein-Barr virus infection
Core Tip	Despite their rarity, lymphoepithelioma-like hepatic carcinomas are of general interest because of their peculiar epidemiological and clinical features, and because they represent a distinct model of interaction between the immune system and neoplastic cells. Compared with classical hepatocellular carcinoma and intrahepatic cholangiocarcinoma of corresponding stage, lymphoepithelioma-like hepatic carcinomas are characterized by lower rates of recurrence after surgery and better overall survival. Whether these differences are related to distinct genetic alterations or to the tumor microenvironment is unclear. Here we review the features of these tumors and the mechanisms of lymphoid infiltration.
Publish Date	2015-03-30 14:23
Citation	Solinas A, Calvisi DF. Lessons from rare tumors: Hepatic lymphoepithelioma-like carcinomas. World J Gastroenterol 2015; 21(12): 3472-3479
URL	http://www.wjgnet.com/1007-9327/full/v21/i12/3472.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i12.3472

Full Article (PDF)	WJG-21-3472.pdf
Full Article (Word)	WJG-21-3472.doc
Manuscript File	14603-Review.docx
Answering Reviewers	14603-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14603-Conflict-of-interest statement.pdf
Copyright License Agreement	14603-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	14603-Language certificate.pdf
Peer-review Report	14603-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	14603-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check	14603-Scientific misconduct check.pdf
Scientific Editor Work List	14603-Scientific editor work list.pdf