| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Novel immunological and nutritional-based prognostic index for gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kai-Yu Sun, Jian-Bo Xu, Shu-Ling Chen, Yu-Jie Yuan, Hui Wu, Jian-Jun Peng, Chuang-Qi Chen, Pi Guo, Yuan-Tao Hao and Yu-Long He |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81101865 |
| National Natural Science Foundation of China |
81272637 |
| Doctoral Fund of the Ministry of Education of China |
20110171120064 |
| Natural Science Foundation of Guangdong Province |
S2013020012724 |
| Clinical Medicine Research Project 5010 of Sun Yat-sen University |
2010006 |
|
| Corresponding Author |
Yu-Long He, MD, PhD, Division of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, 58, Zhongshan Second Road, Guangzhou 510080, Guangdong Province, China. ylh@medmail.com.cn |
| Key Words |
Gastric cancer; Prognostic nutritional index; Canton score; Prognosis; Neutrophil-lymphocyte ratio; Platelet-lymphocyte ratio |
| Core Tip |
This is the first study on comparing the prognostic significance of different immuno-nutritional indices including prognostic nutritional index (PNI), neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in gastric cancer. We found that PNI was an independent prognostic factor for overall survival in gastric cancer before and after the propensity score analysis, especially in patients with advanced disease, deep tumors, or lymph node metastasis. We also proposed a new index-Canton socre (a combination of PNI, NLR and PLT), is a superior prognostic factor compared to PNI, NLR, or PLR alone, as it better represents the relative contribution of each of these indices.
|
| Publish Date |
2015-05-20 17:01 |
| Citation |
Sun KY, Xu JB, Chen SL, Yuan YJ, Wu H, Peng JJ, Chen CQ, Guo P, Hao YT, He YL. Novel immunological and nutritional-based prognostic index for gastric cancer. World J Gastroenterol 2015; 21(19): 5961-5971 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i19/5961.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i19.5961 |
