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4/7/2015 6:08:00 PM | Browse: 1072 | Download: 1169
Publication Name World Journal of Gastroenterology
Manuscript ID 14736
Country/Territory United States
Received
2014-10-25 14:06
Peer-Review Started
2014-10-27 18:04
To Make the First Decision
2014-11-14 18:44
Return for Revision
2014-11-20 09:17
Revised
2014-12-02 05:23
Second Decision
2014-12-26 13:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-01-08 17:24
Articles in Press
2015-01-08 17:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-03-12 09:13
Publish the Manuscript Online
2015-04-07 17:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Case Report
Article Title Resolution of Crohn's disease and complex regional pain syndrome following treatment of paratuberculosis
Manuscript Source Unsolicited Manuscript
All Author List J Todd Kuenstner, William Chamberlin, Saleh A Naser, Michael T Collins, Coad Thomas Dow, John M Aitken, Stuart Weg, Grzegorz Telega, Kuruvilla John, David Haas, Torsten M Eckstein, Maher Kali, Christine Welch and Thomas Petrie
Funding Agency and Grant Number
Corresponding Author J Todd Kuenstner, MD, Department of Pathology, Charleston Area Medical Center, 3200 MacCorkle Ave. SE, Charleston, WV 25304, United States. jtodd.kuenstner@camc.org
Key Words Crohn’s disease; Complex regional pain syndrome; Lymphangiomatosis; Mycobacterium avium paratuberculosis; Cure
Core Tip Five patients with multiple diseases of unknown etiology were found to have evidence of infection by Mycobacterium avium subsp. paratuberculosis (MAP) including positive blood cultures (except in case 4). Two of the cases (case 1 with Crohn’s disease and asthma and case 2 with complex regional pain syndrome, hypothyroidism and Raynaud’s phenomenon) have been treated with a combination of anti-MAP antibiotics and ultraviolet blood irradiation therapy with resolution of the disease symptomatology and inability to culture MAP in post treatment blood samples. These case reports of patients with MAP infections provide supportive evidence of a pathogenic role of MAP in humans.
Publish Date 2015-04-07 17:13
Citation Kuenstner JT, Chamberlin W, Naser SA, Collins MT, Dow CT, Aitken JM, Weg S, Telega G, John K, Haas D, Eckstein TM, Kali M, Welch C, Petrie T. Resolution of Crohn’s disease and complex regional pain syndrome following treatment of paratuberculosis. World J Gastroenterol 2015; 21(13): 4048-4062
URL http://www.wjgnet.com/1007-9327/full/v21/i13/4048.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i13.4048
Full Article (PDF) WJG-21-4048.pdf
Full Article (Word) WJG-21-4048.doc
Manuscript File 14736-Review.doc
Answering Reviewers 14736-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 14736-Conflict-of-interest statement.pdf
Copyright License Agreement 14736-Copyright asssignment.pdf
Institutional Review Board Approval Form or Document 14736-Institutional Review Board (IRB) statement.pdf
Peer-review Report 14736-Peer review(s).pdf
Scientific Misconduct Check 14736-CorssCheck.jpg
Scientific Editor Work List 14736-Scientific editor work list.pdf