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4/27/2015 4:29:00 PM | Browse: 493 | Download: 839
Publication Name World Journal of Gastroenterology
Manuscript ID 14748
Country/Territory China
Received
2014-10-22 21:45
Peer-Review Started
2014-10-28 08:49
To Make the First Decision
2014-12-11 20:20
Return for Revision
2014-12-24 08:57
Revised
2015-01-04 16:06
Second Decision
2015-02-10 21:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-02-11 15:01
Articles in Press
2015-02-11 16:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-03-10 17:46
Typeset the Manuscript
2015-04-14 15:50
Publish the Manuscript Online
2015-04-27 16:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medical Laboratory Technology
Manuscript Type Basic Study
Article Title Comparison of two different laparotomy methods for modeling rabbit VX2 hepatocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Zhu Chen, Zhen Kang, En-Hua Xiao, Min Tong, Yu-Dong Xiao and Hua-Bing Li
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Hunan Province, China 14JJ2034
Development and Reform Commission of Hunan Province, China 2013-1199
Science and Technology Department of Hunan Province, China 2014TT2017
Corresponding author En-Hua Xiao, MD, Professor, Department of Radiology, the Second Xiangya Hospital, Central South University, No. 139 Renmin Zhong Lu, Fu Rong District, Changsha 410011, Hunan Province, China. cjr.xiaoenhua@vip.163.com
Keywords Rabbit VX2 hepatocarcinoma; Laparotomy; Modeling; Magnetic resonance imaging
Core Tip A crucial issue in studying liver cancer is the establishment of an animal model to simulate human liver cancer. There are various ways to establish rabbit VX2 hepatocarcinoma, and using an open laparotomy implant is a widely adopted classical method. We injected tumor fragments into the left lobe of the rabbit liver, deviating from the abdominal wall using a 15 G syringe needle instead of building a sinus using tweezers. This improved method is recommended because of advantages such as decreased injury to the liver, shorter operation time, lower death rates, reduced abdominal cavity implantation and fewer abdominal wall invasions.
Publish Date 2015-04-27 16:22
Citation Chen Z, Kang Z, Xiao EH, Tong M, Xiao YD, Li HB. Comparison of two different laparotomy methods for modeling rabbit VX2 hepatocarcinoma. World J Gastroenterol 2015; 21(16): 4875-4882
Url http://www.wjgnet.com/1007-9327/full/v21/i16/4875.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i16.4875
Full Article (PDF) WJG-21-4875.pdf
Full Article (Word) WJG-21-4875.doc
Manuscript File 14748-Review.doc
Answering Reviewers 14748-Answering reviewers.pdf
Biostatistics Review Certificate 14748-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 14748-Conflict-of-interest statement.pdf
Copyright License Agreement 14748-Copyright assignment.pdf
Data Sharing Statement 14748-Data sharing statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 14748-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 14748-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 14748-Language certificate.pdf
Peer-review Report 14748-Peer-review(s).pdf
Scientific Misconduct Check 14748-Scientific misconduct check.pdf
Scientific Editor Work List 14748-Scientific editor work list.pdf