Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	14981
Country	Italy

Received	2014-11-03 08:36
Peer-Review Started	2014-11-04 20:25
To Make the First Decision	2014-11-27 12:06
Return for Revision	2014-12-26 10:51
Revised	2015-01-07 01:17
Second Decision	2015-02-27 09:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-03-09 16:51
Articles in Press	2015-03-09 16:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-15 14:31
Publish the Manuscript Online	2015-05-18 11:00

ISSN	2219-2808 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Appendicitis in children less than five years old: A challenge for the general practitioner
Manuscript Source	Invited Manuscript
All Author List	Pierluigi Marzuillo, MD, Department of Women and Children and General and Specialized Surgery, Seconda Università degli Studi di Napoli, Via L. De Crecchio 2, 80138 Naples and Italy. pierluigi.marzuillo@gmail.com
Funding Agency and Grant Number
Corresponding Author	Pierluigi Marzuillo, MD, Department of Women and Children and General and Specialized Surgery, Seconda Università degli Studi di Napoli, Via L. De Crecchio 2, 80138 Naples, Italy. pierluigi.marzuillo@gmail.com
Key Words	Appendicitis; Children; Early diagnosis; Newborn; Appendicitis complications
Core Tip	Acute appendicitis in the first years of life is an uncommon event but with a high incidence of early perforation the younger the patient. We highlight the epidemiology, pathophysiology, clinical signs, and laboratory clues of appendicitis in young children. The challenge for the practitioner is to perform a timely diagnosis of acute appendicitis in first years of life before complications occur.
Publish Date	2015-05-18 11:00
Citation	Marzuillo P, Germani C, Krauss BS, Barbi E. Appendicitis in children less than five years old: A challenge for the general practitioner. World J Clin Pediatr 2015; 4(2): 19-24
URL	http://www.wjgnet.com/2219-2808/full/v4/i2/19.htm
DOI	http://dx.doi.org/10.5409/wjcp.v4.i2.19

Full Article (PDF)	WJCP-4-19.pdf
Full Article (Word)	WJCP-4-19.doc
Manuscript File	14981-Review.doc
Answering Reviewers	14981-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14981-Conflict-of-interest statement.pdf
Copyright License Agreement	14981-Copyright assignment.pdf
Peer-review Report	14981-Peer-review(s).pdf
Scientific Misconduct Check	14981-Scientific misconduct check.pdf
Scientific Editor Work List	14981-Scientific editor work list.pdf